pyrocatechol violet

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: pyrocatechol violet
• 英文别名: Brenzkatechinviolett；2-[(Z)-(3,4-dihydroxyphenyl)-(3-hydroxy-4-oxoniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate
• 化学式: C₁₉H₁₄O₇S
• 分子量: 386.382
• InChiKey: HGPSVOAVAYJEIJ-UNOMPAQXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  141
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  pyrocatechol violet 在 buffer solution 作用下， 生成 Brenzcatechin-sulfophthalein
  参考文献：
  名称：

  Abdel-Hamid, Refat, journal of the chemical society-perkin transactions 2, 1996, vol. 4, p. 691 - 696

  摘要：

  DOI：

文献信息

• Self-contained phosphate sensors and method for using same
  申请人：Xiao Caibin

  公开号：US20070092972A1

  公开（公告）日：2007-04-26

  Embodiments of the invention provide self-contained phosphate sensors with an analyte-specific reagent and a pH-modifier. The analyte-specific reagent includes a molybdenum salt or metal complex and a dye. The self-contained phosphate sensors can be used either in aqueous or non-aqueous solution or as a solid-state device. These self-contained phosphate sensors require no post-addition reagents to determine phosphate concentrations and the phosphate determination test requires a reduced number of procedural steps. Moreover, the self-contained phosphate sensor provides enhanced sensitivity and faster response time. Embodiments of the invention also provide a method for determining phosphate concentrations in a sample. The phosphate concentration in a sample can be quantified using a calibration curve generated by testing samples with known phosphate concentrations.

  本发明实施例提供了具有特定分析物试剂和pH调节剂的自包含磷酸盐传感器。分析物特异性试剂包括钼盐或金属配合物和染料。自包含磷酸盐传感器可用于水溶液或非水溶液或作为固态装置。这些自包含磷酸盐传感器不需要添加后续试剂来确定磷酸盐浓度，而磷酸盐测定测试需要较少的程序步骤。此外，自包含磷酸盐传感器提供了增强的灵敏度和更快的响应时间。本发明实施例还提供了一种确定样品中磷酸盐浓度的方法。可以使用通过测试已知磷酸盐浓度样品生成的校准曲线来量化样品中的磷酸盐浓度。
• Pyrocatechol Violet in Pharmaceutical Analysis Part II. A Spectrophotometric Method for the Determination of Paracetamol in Pure and in Pharmaceutical Dosage Forms
  作者：Alaa Amin

  DOI：10.3797/scipharm.aut-01-19

  日期：——

  A spectrophotometric method for the selective determination of paracetamol based on its reaction with pyrochatechol violet under basic conditions to form an ion-pair complex is described. The absorption maximum of the coloured ion-pair formed is observed at 652 nm and the molar absorptivity is 4.54 x10-3l mol-1 cm-1. Beer's law is obeyed over the concentration range 0.5-34.0 μg ml-1, while that obtained using Ringbom method is in the range 3.5 -32.0 μg ml-1. There is no interference from common additives, excipients and commercial drugs present in their formulations suggesting a highly selective procedure compared with others. Statistical analysis of the obtained results showed that there is, no significant difference and absence of any systematic error in the method compared with the official one. The method is simple, rapid and convenient and was applied successfully to the determination of paracetamol in pure and in its dosage forms compared with the official method.

  描述了一种选择性测定扑热息痛的分光光度法，该方法基于扑热息痛在碱性条件下与焦儿茶酚紫反应形成的离子对复合物。所形成的有色离子对的最大吸收波长为 652 nm，摩尔吸收率为 4.54 x10-3l mol-1 cm-1。在 0.5-34.0 μg ml-1 的浓度范围内符合比尔定律，而使用林格邦法得到的浓度范围为 3.5-32.0 μg ml-1。与其他方法相比，它们的配方中没有常见添加剂、辅料和商业药物的干扰，这表明该方法具有高度的选择性。对所得结果的统计分析表明，该方法与官方方法相比没有显著差异，也不存在任何系统误差。该方法简单、快速、方便，与官方方法相比，成功地应用于扑热息痛纯品及其剂型的测定。
• Corrosion inhibiting sol-gel compositions
  申请人：PRC-DeSoto International, Inc.

  公开号：US10370765B2

  公开（公告）日：2019-08-06

  A composition for application to a metal substrate comprises a sol-gel or a silane and a corrosion inhibitor. The corrosion inhibitor comprises a lithium ion and/or an azole compound. A coated substrate includes the composition for application to a metal substrate and a coating on the composition. A method of fabricating a coated substrate comprises applying the composition to a substrate, curing the composition to form a conversion coating, and applying a coating on the conversion coating.

  一种用于金属基底的组合物由溶胶-凝胶或硅烷和腐蚀抑制剂组成。缓蚀剂包括锂离子和/或唑化合物。涂层基底包括用于金属基底的组合物和组合物上的涂层。制造涂覆基底的方法包括将组合物涂到基底上，固化组合物以形成转化涂层，以及在转化涂层上涂覆涂层。
• MATERIAL COMPOSITIONS FOR SENSORS FOR DETERMINATION OF CHEMICAL SPECIES AT TRACE CONCENTRATIONS AND METHOD OF USING SENSORS
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP1949092B1

  公开（公告）日：2017-08-02
• Determining Enantiomeric Excess Using Indicator-Displacement Assays
  申请人：Anslyn V. Eric

  公开号：US20070292968A1

  公开（公告）日：2007-12-20

  The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined. The assay may involve two independent absorption measurements. On suitable group of enantiomeric molecules to be assayed include α-hydroxyacids. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte is established through solution equilibria. The invention also includes use of the assay in drug screening and manufacturing, high throughput screening of catalysts and kits for use in conducting assays of the invention.