4'-bromo-[1,1'-biphenyl]-4-yl formate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4'-bromo-[1,1'-biphenyl]-4-yl formate
• 英文别名: [4-(4-Bromophenyl)phenyl] formate
• 化学式: C₁₃H₉BrO₂
• 分子量: 277.117
• InChiKey: JNWAWWUEYFCMQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-羟基-4'-溴联苯 、 sodium chlorodifluoroacetate 在 sodium carbonate 作用下， 以 乙腈 为溶剂， 以54 %的产率得到4'-bromo-[1,1'-biphenyl]-4-yl formate
  参考文献：
  名称：

  使用二氟卡宾作为安全的 CO 替代物直接甲酰化苯酚

  摘要：

  本文报道了一种制备甲酸芳酯的便捷方法，该方法利用二氟卡宾作为 CO 替代物。该反应被认为是通过苯酚的顺序O-二氟甲基化，然后通过苯酚或水分通过氟半缩醛或原甲酸酯中间体对所得芳基二氟甲基醚中间体进行 α-C-F 键官能化而发生的。证明了生物和材料活性化合物的后期修饰。

  DOI：

  10.1039/d2ob02128e

文献信息

• Preparation of cis-olefins
  申请人：NISSAN CHEMICAL INDUSTRIES LTD.

  公开号：EP0560532A1

  公开（公告）日：1993-09-15

  A method for preparing a cis-olefin of the formula : R1-CH=CH-R2 by reducing an alkyne of the formula: R1-C≡C-R2 with formic acid in the presence of a palladium catalyst. R1 and R2 are independently selected from the group consisting of a hydrogen atom, ester group, substituted silyl group, carboxyl group, cyano group, aliphatic CI-C20 hydrocarbon group, and phenyl group. The cis-olefin which is a useful intermediate for the synthesis of fine chemicals is selectively produced in high yields.

  一种制备式......的顺式烯烃的方法 R1-CH=CH-R2 的顺式烯烃的制备方法： R1-C≡C-R2 在钯催化剂存在下用甲酸还原。R1 和 R2 独立地选自氢原子、酯基、取代的硅烷基、羧基、氰基、脂肪族 CI-C20 烃基和苯基组成的组。这种顺式烯烃是合成精细化学品的有用中间体，可选择性地以高产率生产。
• LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME
  申请人：Tanaka Kenta

  公开号：US20110177312A1

  公开（公告）日：2011-07-21

  A laminated structure comprising an electrode, a polymer binding layer arranged on the electrode, and an electrically conductive organic material layer arranged on the polymer binding layer, wherein the polymer binding layer comprises an aromatic polymeric compound which has a structure represented by formula (I) [wherein Ar represents a conjugated divalent group which may have a substituent, provided that when there are multiple Ar's, the Ar's may be the same as or different from each other; and n represents an integer of 1 or greater] and has a number average molecular weight of 1×10 3 to 1×10 8 inclusive in terms of polystyrene content, the polymer binding layer is bonded to the electrode via a chemical bond between the aromatic polymeric compound and the surface of the electrode, and an electrically conductive organic material that composes a layer included in the electrically conductive organic material layer and arranged adjacent to the polymer binding layer has a number average molecular weight of 3×10 2 to 1×10 8 inclusive in terms of polystyrene content.
• US6333441B1
  申请人：——

  公开号：US6333441B1

  公开（公告）日：2001-12-25
• Direct formylation of phenols using difluorocarbene as a safe CO surrogate
  作者：Cong-Cong Feng、Song-Lin Zhang

  DOI：10.1039/d2ob02128e

  日期：——

  A convenient method to prepare aryl formates is reported herein that exploits difluorocarbene to serve as a CO surrogate. This reaction is proposed to occur through a sequential O-difluoromethylation of phenol, followed by α-C–F bond functionalization of the resulting aryl difluoromethyl ether intermediate by phenol or moisture through fluorosemiacetal or orthoformate intermediates. Late-stage modification

  本文报道了一种制备甲酸芳酯的便捷方法，该方法利用二氟卡宾作为 CO 替代物。该反应被认为是通过苯酚的顺序O-二氟甲基化，然后通过苯酚或水分通过氟半缩醛或原甲酸酯中间体对所得芳基二氟甲基醚中间体进行 α-C-F 键官能化而发生的。证明了生物和材料活性化合物的后期修饰。