dimethyl-(2-bromomethyl)benzeneboronate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dimethyl-(2-bromomethyl)benzeneboronate
• 英文别名: [2-(Bromomethyl)phenyl]-dimethoxyborane；[2-(bromomethyl)phenyl]-dimethoxyborane
• 化学式: C₉H₁₂BBrO₂
• 分子量: 242.908
• InChiKey: USRSPYDBEKNPCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.57
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4,4'-联吡啶 、 dimethyl-(2-bromomethyl)benzeneboronate 以 甲醇 为溶剂， 反应 15.0h， 以70%的产率得到N,N'-bis-(benzyl-2-boronic acid)-[4,4']bipyridinium dibromide
  参考文献：
  名称：

  Boronic acid substituted viologen based optical sugar sensors: modulated quenching with viologen as a method for monosaccharide detection

  摘要：

  In our search for an optical glucose sensor we have found that the combination of pyranine I and a boronic acid substituted benzyl viologen (o-BBV. 2) signals in monosaccharides in the range of 0 1800 mg/dL. The quenching ability of o-BBV is modulated upon sugar binding. which in turn alters the fluorescence of pyranine. The system utilizes a dye that is active in the visible spectrum, operates in aqueous solution at pH 7.4, and is highly sensitive to glucose in the physiological range. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)02366-8