2-(2,4,6-triisopropylphenylsulfonamido)benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2,4,6-triisopropylphenylsulfonamido)benzamide
• 英文别名: 2-[[2,4,6-Tri(propan-2-yl)phenyl]sulfonylamino]benzamide
• 化学式: C₂₂H₃₀N₂O₃S
• 分子量: 402.558
• InChiKey: RVJPQSGPVKDYLL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  97.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙腈 、 palladium diacetate 、 2-(2,4,6-triisopropylphenylsulfonamido)benzamide 以 乙醚 为溶剂， 反应 504.0h， 生成
  参考文献：
  名称：

  N-donor 2-(Sulfonamido)benzamide ligands, their palladium(II) coordination species and C–C coupling catalysis efficiencies

  摘要：

  A series of synthetically accessible ligands based on new 2-(R-sulfonamido)benzamide have been prepared (R = methyl for H3M; R = 4-toly for H3T and T2CN; R = 2,4,6-triisopropylphenyl for H(3)iP and HiPCN). The R-substituents were selected to vary in sizes. Allowing ligand H(3)iP and palladium acetate to stand in solvent leads to self-assembly of the well-defined solvent- and stoichiometry-controlled tetranuclear or hexanuclear coordination macromolecules Pd-4(iP)(2) and (PdHiP)(6), which were analysed by X-ray crystallography. It was observed that palladium active species for Suzuki coupling catalysis could be stabilized by these simple and synthetically assessable N-donor ligands as revealed by turnover frequencies reaching 5500h(-1). Electronic features of these N-donors appear to be more important than the steric properties. (C) 2019 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2019.07.054