cyclohexyl 4-ethylbenzoate | 959111-34-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: cyclohexyl 4-ethylbenzoate
• 英文别名: 4-Ethylbenzoic acid, cyclohexyl ester
• CAS: 959111-34-3
• 化学式: C₁₅H₂₀O₂
• 分子量: 232.323
• InChiKey: CLJHCDQZMAMGTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-(trifluoromethanesulfonyloxy)benzoic acid cyclohexyl ester 、 [1,3-Bis[2,6-di(propan-2-yl)phenyl]imidazol-1-ium-2-yl]-triethylboranuide 在 palladium diacetate 、 2-二环己基磷-2,4,6-三异丙基联苯 作用下， 以 水 、 甲苯 为溶剂， 反应 24.0h， 以99%的产率得到cyclohexyl 4-ethylbenzoate
  参考文献：
  名称：

  Suzuki−Miyaura Coupling of NHC−Boranes: A New Addition to the C−C Coupling Toolbox

  摘要：

  Complexes of triaryl- and trialkylboranes with N-heterocyclic carbenes (NHCs) participate in Suzuki-Miyaura cross-coupling reactions and provide coupled products in good yields under base-free conditions. The reaction can be applied to CSp(2)-CSp(2) and Csp(2)-Csp(2) carbon-carbon bond formation with triflates, iodides, bromides, and chlorides. These results enrich the utility of NHC-borane complexes, which can be added to the toolkit of Suzuki-Miyaura cross-couplings, along with boronic acids and organotrifluoroborates.

  DOI：

  10.1021/ol902012c

文献信息

• [EN] SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS<br/>[FR] AGENTS SOLUBILISANTS POUR COMPOSÉS ACTIFS FONCTIONNELS
  申请人：ISP INVESTMENTS INC

  公开号：WO2016201260A1

  公开（公告）日：2016-12-15

  A photo protective topical composition, comprising: (i) at least one functional active; and (ii) at least one solubilizing compound having the structure of Formula (I): wherein R is C5-C10 cycloalkyl or linear or branched alkylcycloalkyl, wherein the ring size is C5-C7; R1, R2, and R3 are each independently selected from the group consisting of H, and linear or branched C1-C4 alkyl, provided that at least two of R1, R2, R3 are H; wherein the solubilizing compound is present in an amount effective to solubilize said functional active. Also disclosed is a method for treating skin, lips, nails, hair, ears, eyelashes, eyebrows and/or scalp with an effective amount of composition.

  一种光保护性局部组合物，包括：（i）至少一种功能活性物质；和（ii）具有以下结构的至少一种溶解化合物（I）：其中R为C5-C10环烷基或直链或支链烷基环烷基，其中环大小为C5-C7；R1、R2和R3分别独立地选择自H、直链或支链C1-C4烷基的群，但至少两个R1、R2、R3为H；其中所述溶解化合物以有效量存在，以溶解所述功能活性物质。还公开了一种使用有效量的组合物治疗皮肤、嘴唇、指甲、头发、耳朵、睫毛、眉毛和/或头皮的方法。
• SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS
  申请人：ISP Investments LLC

  公开号：EP3307395B1

  公开（公告）日：2020-08-05