4,4'-diamino-benzophenone-imine | 24646-83-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-diamino-benzophenone-imine
• 英文别名: 4,4'-Diamino-benzophenon-imin；4.4'-Diamino-benzophenon-imid；4-(4-Aminobenzenecarboximidoyl)aniline
• CAS: 24646-83-1
• 化学式: C₁₃H₁₃N₃
• 分子量: 211.266
• InChiKey: XGDKPTLPDOUVNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.9
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4,4'-diamino-benzophenone-imine 在 ammonium sulfide 、 硫化氢 作用下， 生成 4,4'-diaminothiobenzophenone
  参考文献：
  名称：

  Madelung, Journal fur praktische Chemie (Leipzig 1954), 1926, vol. <2> 114, p. 46

  摘要：

  DOI：

文献信息

• NAPHTHALENE-BASED INHIBITORS OF ANTI-APOPTOTIC PROTEINS
  申请人：Pellecchia Maurizio

  公开号：US20090105319A1

  公开（公告）日：2009-04-23

  Methods of using apogossypol and its derivatives for treating inflammation is disclosed. Also, there is described a group of compounds having structure A, or a pharmaceutically acceptable salt, hydrate, N-oxide, or solvate thereof are provided: wherein each R is independently selected from the group consisting of H, C(O)X, C(O)NHX, NH(CO)X, SO 2 NHX, and NHSO 2 X, wherein X is selected from the group consisting of an alkyl, a substituted alkyl, an aryl, a substituted aryl, an alkylaryl, and a heterocycle. Compounds of group A may be used for treating various diseases or disorders, such as cancer.

  使用阿波戈司宝及其衍生物治疗炎症的方法被披露。此外，还描述了一组具有结构A的化合物，或其药学上可接受的盐、水合物、N-氧化物或溶剂化合物： 其中每个R独立地选自H、C(O)X、C(O)NHX、NH(CO)X、SO2NHX和NHSO2X组成的组，其中X选自烷基、取代烷基、芳基、取代芳基、烷基芳基和杂环的组。A组化合物可用于治疗各种疾病或疾病，如癌症。
• Nucleic acid labeling compounds
  申请人：McGall H. Glenn

  公开号：US20050003496A1

  公开（公告）日：2005-01-06

  Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. Methods for making such heterocyclic compounds are also disclosed. The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

  揭示了含有杂环衍生物的核酸标记化合物。还公开了制备这种杂环化合物的方法。这些标记化合物适用于通过酶的附着，无论是末端还是内部，提供核酸检测的机制。
• REAGENTS FOR LABELLING NUCLEIC ACIDS AND USES THEREOF
  申请人：Mouritzen Peter

  公开号：US20090023594A1

  公开（公告）日：2009-01-22

  The present invention relates to labelling kits containing novel non-natural nucleotide monomers and to methods of making and using such compounds. The invention further relates to a method of detecting the presence of a nucleic acid, e.g., RNA, of interest in a sample, the method having the following steps: providing the sample; ligating a nucleic acid of interest with a labelling reagent according to the instant invention; providing a nucleic acid array having probes directed to the nucleic acid of interest; hybridizing the labelled nucleic acid fragments to said nucleic acid array; and determining the extent of hybridization to said probes to determine the presence of the nucleic acid of interest.

  本发明涉及包含新型非自然核苷酸单体的标记试剂盒以及制备和使用这些化合物的方法。本发明还涉及一种检测样品中感兴趣的核酸（例如RNA）存在的方法，该方法包括以下步骤：提供样品；使用本发明的标记试剂将感兴趣的核酸连接起来；提供具有针对感兴趣的核酸的探针的核酸阵列；将标记的核酸片段杂交到该核酸阵列上；并确定杂交到探针的程度以确定感兴趣的核酸是否存在。
• NUCLEIC ACID LABELING COMPOUNDS
  申请人：——

  公开号：US20010018514A1

  公开（公告）日：2001-08-30

  Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

  本发明揭示了含有杂环衍生物的核酸标记化合物。这些含有杂环衍生物的化合物是通过将杂环衍生物与环状基团（例如核糖呋喃衍生物）缩合而合成的。这些标记化合物适用于酶促连接到核酸上，无论是末端或内部，以提供核酸检测的机制。
• Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
  申请人：——

  公开号：US20030119021A1

  公开（公告）日：2003-06-26

  Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Automated systems for performing the methods also provided.

  提供了用于分析生物分子的捕获化合物和化合物集合以及使用这些化合物的方法。特别是，提供了用于分析复杂蛋白质混合物（如蛋白质组）的集合、化合物和方法。这些化合物是多功能试剂，可用于分离和分离复杂蛋白质混合物。还提供了执行这些方法的自动化系统。