5-hexadecanoyloxymethyl-3-hydroxy-4-hydroxymethyl-2-methylpyridine | 14210-75-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-hexadecanoyloxymethyl-3-hydroxy-4-hydroxymethyl-2-methylpyridine
• 英文别名: Pyridoxol-5'-palmitat, 2-Methyl-3-hydroxy-4-hydroxymethyl-5-palmitoyloxymethyl-pyridin；α⁵-O-Palmitoylpyridoxol；5-hexadecanoyloxymethyl-4-hydroxymethyl-2-methyl-pyridin-3-ol；4-hydroxymethyl-2-methyl-5-palmitoyloxymethyl-pyridin-3-ol；[5-Hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyl hexadecanoate
• CAS: 14210-75-4
• 化学式: C₂₄H₄₁NO₄
• 分子量: 407.594
• InChiKey: PFZXGXCGOJDNRF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  29
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  79.6
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,2,8-三甲基-4H-1,3-二恶英并[4,5-c]吡啶-5-甲醇 在 盐酸 作用下， 以 吡啶 、 乙醇 为溶剂， 反应 97.5h， 生成 5-hexadecanoyloxymethyl-3-hydroxy-4-hydroxymethyl-2-methylpyridine
  参考文献：
  名称：

  Brown, Linda; Johnston, Grant A.; Suckling, Colin J., Journal of the Chemical Society. Perkin transactions I, 1993, # 22, p. 2777 - 2780

  摘要：

  DOI：

文献信息

• AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION AND ANTI-AGING COMPOSITION
  申请人：Showa Denko K.K.

  公开号：EP3213739A1

  公开（公告）日：2017-09-06

  Provided is an agent for improving mitochondrial function including a hydroxycitric acid derivative represented by the following Formula (I) or a salt thereof, as an active ingredient [(In Formula (I), R1 and R2 each independently represent a hydrogen atom or any one group selected from the group represented by the following Formula (Ia) (here, R1 and R2 do not represent hydrogen atoms at the same time), X1 to X3 each independently represent a nitrogen or an oxygen atom, and R3, R4, R5, R3', R4', and R5' each independently represent a hydrogen atom, or a chained hydrocarbon group (here, in a case where X1, X2, and X3 each independently represent an oxygen atom, corresponding R3', R4', or R5' does not exist). In Formula (Ia), R6 to R8 each independently represent a hydrogen atom, an aryl group, or a chained hydrocarbon group having 1 to 30 carbon atoms].

  提供了一种改善线粒体功能的制剂，包括由下式(I)代表的羟基柠檬酸衍生物或其盐，作为活性成分[(在式(I)中，R1和R2各自独立地代表氢原子或选自下式(Ia)所代表的基团中的任意一个基团（此处、R1和R2不同时代表氢原子），X1至X3各自独立地代表氮原子或氧原子，R3、R4、R5、R3'、R4'和R5'各自独立地代表氢原子或链状烃基（此处，在X1、X2和X3各自独立地代表氧原子的情况下，不存在相应的R3'、R4'或R5'）。在式 (Ia)中，R6 至 R8 各自独立地代表氢原子、芳基或具有 1 至 30 个碳原子的链状烃基]。
• SKIN BARRIER FUNCTION-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN BARRIER FUNCTION
  申请人：Showa Denko K.K.

  公开号：EP3213753A1

  公开（公告）日：2017-09-06

  The present invention provides a skin barrier function-improving agent including an inositol derivative as an active ingredient in which inositol and saccharide are bonded, and a composition for improving a skin barrier function including the above skin barrier function-improving agent and a pharmacologically acceptable carrier.

  本发明提供了一种皮肤屏障功能改善剂，其中包括一种以肌醇衍生物为活性成分、肌醇和糖键合的皮肤屏障功能改善剂，以及一种用于改善皮肤屏障功能的组合物，其中包括上述皮肤屏障功能改善剂和药理学上可接受的载体。
• MOISTURIZING AGENT
  申请人：Showa Denko K.K.

  公开号：EP3219304A1

  公开（公告）日：2017-09-20

  The present invention provides a moisturizing agent including an inositol derivative as an active ingredient in which saccharide of three or more monosaccharide unit is bonded to per molecule of inositol.

  本发明提供了一种包括肌醇衍生物作为活性成分的保湿剂，其中每个肌醇分子都键合了三个或三个以上单糖单元的糖。
• METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC
  申请人：Adeka Corporation

  公开号：EP3578161A1

  公开（公告）日：2019-12-11

  The purpose of this invention is to provide a method for stabilizing a cosmetic over a long period of time. In order to achieve this purpose, this invention provides a method for improving the storage stability of a cosmetic, the method including blending a compound represented by the following general formula (1). (In formula (1), R1 represents a group represented by general formula (2) or a hydrocarbon group having 2 or 3 carbon atoms.) (In formula (2), R2 represents an alkylene group having 1 to 3 carbon atoms, and n represents an integer of 0 or 1.)

  本发明的目的是提供一种长期稳定化妆品的方法。为实现这一目的，本发明提供了一种提高化妆品贮存稳定性的方法，该方法包括混合由以下通式（1）代表的化合物。 (在式 (1) 中，R1 代表通式 (2) 所代表的基团或具有 2 或 3 个碳原子的烃基）。 式（2）中，R2 代表具有 1 至 3 个碳原子的亚烷基，n 代表 0 或 1 的整数）。
• COSMETIC EMULSION COMPOSITION
  申请人：ADEKA CORPORATION

  公开号：EP3603609A1

  公开（公告）日：2020-02-05

  An object of the present invention is to provide a cosmetic emulsion composition that satisfies all of the properties of usability, use sensation, and transparency in appearance. In order to achieve this object, the present invention provides a cosmetic emulsion composition that contains (A) a component containing a monoalkyl glyceryl ether having a C6-8 alkyl group and (B) a component containing an associative urethane.

  本发明的目的是提供一种化妆品乳液组合物，该组合物满足可用性、使用感和外观透明性的所有特性。为了实现这一目标，本发明提供了一种化妆品乳液组合物，它包含（A）一种含有具有 C6-8 烷基的单烷基甘油醚的成分和（B）一种含有缔合聚氨酯的成分。