(E)-4-(((4-hydroxybenzyl)imino)methyl)-2-methoxyphenol | 1393660-50-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (E)-4-(((4-hydroxybenzyl)imino)methyl)-2-methoxyphenol
• CAS: 1393660-50-8
• 化学式: C₁₅H₁₅NO₃
• 分子量: 257.289
• InChiKey: AOFFIGJHWLPQAO-MHWRWJLKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.73
• 重原子数：
  19.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  62.05
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  (E)-4-(((4-hydroxybenzyl)imino)methyl)-2-methoxyphenol 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 以85%的产率得到4-(((4-hydroxybenzyl)amino)methyl)-2-methoxyphenol
  参考文献：
  名称：

  Synthesis of [2]Catenanes by Template-Directed Clipping Approach

  摘要：

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.

  DOI：

  10.1021/jo3012804
• 作为产物：
  描述：

  4-羟基苄胺 、 香草醛 在 magnesium sulfate 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以89%的产率得到(E)-4-(((4-hydroxybenzyl)imino)methyl)-2-methoxyphenol
  参考文献：
  名称：

  Synthesis of [2]Catenanes by Template-Directed Clipping Approach

  摘要：

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.

  DOI：

  10.1021/jo3012804