p-N,N-dimethylamino benzamidopropyldimethylamine | 92430-96-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-N,N-dimethylamino benzamidopropyldimethylamine
• 英文别名: 4-(dimethylamino)-N-[3-(dimethylamino)propyl]benzamide
• CAS: 92430-96-1
• 化学式: C₁₄H₂₃N₃O
• mdl: MFCD01216802
• 分子量: 249.356
• InChiKey: MLHNBZURMBFIKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  p-N,N-dimethylamino benzamidopropyldimethylamine 、 1-氯代二十二碳烷 反应 15.0h， 以96%的产率得到p-N,N-dimethylamino-benzamidopropyldimethylbehenylammonium chloride
  参考文献：
  名称：

  UV-absorbing lipid vesicles

  摘要：

  本发明描述了从吸收紫外线的脂质中高效制备的囊泡组合物。吸收紫外线的特性和囊泡输送系统的结合导致对皮肤和头发的光保护水平更高。本发明的囊泡组合物是由公式I的阳离子吸收紫外线脂质制成，其中ArCO选择自肉桂酰基，对甲氧基肉桂酰基，对N，N-二甲基氨基苯甲酰基和其组合物，R1选择自碳数范围为C10到C22的饱和或不饱和烷基。

  公开号：

  US20060067893A1

文献信息

• Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and/or benzamidoalkylamines
  申请人：Koshti Madhukar Nirmal

  公开号：US20050080135A1

  公开（公告）日：2005-04-14

  An efficient, simple, high yielding, eco-friendly process for the manufacture of tosylates quaternary ammonium salts of cinnamidoalkylamines and/or benzamidoalkylamines (Formula I) has been described. These compounds are substantive UV-absorbers. They are useful in making fabric care products and personal care products. The scope of this methodology has been demonstrated by converting water soluble organic sunscreen quaternary halides to their corresponding tosylates of Formula VI.

  一种高效、简单、高产率、环保的方法用于制造肉桂酰基烷基胺和/或苯甲酰基烷基胺的甲基磺酸盐季铵盐（公式I）。这些化合物是有实质性UV吸收剂。它们在制造织物护理产品和个人护理产品方面非常有用。通过将水溶性有机防晒剂季铵卤化物转化为其相应的公式VI的甲基磺酸盐，证明了该方法的适用范围。
• Quaternary salts of para-dialkylamino benzamide derivatives
  申请人：ISP Van Dyk Inc.

  公开号：US05451394A1

  公开（公告）日：1995-09-19

  This invention relates to non-hydrolyzable, non-irritating, hair, skin and textile substantive quaternary ammonium salts of a para-dialkylamino benzamide having the formula ##STR1## wherein R' and R" are each selected from the group of C.sub.1 to C.sub.2 alkyl; n is an integer having a value of from 2 to 6; R is an alkyl radical having from 1 to 30 carbon atoms; R.sub.1 and R.sub.2 are each selected from the group of C.sub.1 to C.sub.4 alkyl, hydrogen and, alternatively, R.sub.1 and R.sub.2, together with the attached cationic nitrogen atom can form a 5 to 6-membered heterocyclic ring selected from the group of ##STR2## and X is an anion. These benzamide derivatives are active sunscreening agents which are usefully employed at a concentration of from about 0.5 to about 10 wt. % in a formulation requiring protection against the harmful effects of sunlight, such as skin burn, hair damage, color fading, etc.

  本发明涉及一种对头孢二甲基氨基苯酰胺的非水解、非刺激、对头发、皮肤和纺织品有实质作用的季铵盐，其具有以下结构式：##STR1## 其中R'和R"分别选择自C.sub.1到C.sub.2烷基的一组；n是一个整数，取值范围为2到6；R是具有1到30个碳原子的烷基基团；R.sub.1和R.sub.2分别选择自C.sub.1到C.sub.4烷基、氢和/或R.sub.1和R.sub.2与附加的阳离子氮原子一起可以形成选择自##STR2## 的5到6元杂环环；X是一个阴离子。这些苯甲酰胺衍生物是活性防晒剂，可在需要保护免受阳光有害影响的配方中浓度为约0.5至约10重量％使用，例如皮肤灼伤、头发损伤、色彩褪色等。
• Salt and heat sensitive, substantive UV-absorbing polymers
  申请人：Galaxy Surfactants Ltd.

  公开号：US20040101498A1

  公开（公告）日：2004-05-27

  Substantive UV-absorbing, water-soluble, cationic polymers containing cinnamidoalkylamines and benzamidoalkylainines, with ‘inverse temperature dependant solubility’ are described in the present invention. They are water-soluble at ambient conditions and yet they are water-resistant at the temperature of human body as well as in the presence of electrolytes. These properties make these macromolecules useful for personal care as well as fabric care products. The present invention also describes the hair, skin and fabric care compositions containing the said polymers of Formula I wherein, ArCO is an UV-absorbing moiety of an organic sunscreen acid or mixtures of organic sunscreen acids selected from p-methoxy cinnamic acid and p-dimethyl amino benzoic acid; R 2 and R 3 are selected from hydrogen, alkyl and cycloalkyl group containing from 1 to 6 carbon atoms; m is an integer from 5 to 9 and n is an integer between 1 to 5 and m+n=10. 1

  本发明描述了含有肉桂基烷基胺和苯甲酰胺基烷基胺的具有 "反温度溶解度 "的实质性紫外线吸收、水溶性阳离子聚合物。它们在环境条件下可溶于水，但在人体温度和电解质存在下却具有防水性。这些特性使这些大分子可用于个人护理和织物护理产品。 本发明还描述了含有上述式 I 聚合物的头发、皮肤和织物护理组合物，其中，ArCO 是选自对甲氧基肉桂酸和对二甲基氨基苯甲酸的有机防晒酸或有机防晒酸混合物的紫外线吸收分子；R 2 和 R 3 选自氢、含 1 至 6 个碳原子的烷基和环烷基；m 是 5 至 9 之间的整数，n 是 1 至 5 之间的整数，m+n=10。 1
• Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and / or benzamidoalkylamines
  申请人：Koshti Madhukar Nirmal

  公开号：US20050209327A1

  公开（公告）日：2005-09-22

  An efficient, simple, high yielding, eco-friendly process for the manufacture of tosylates quaternary ammonium salts of cinnamidoalkylamines and/or benzamidoalkylamines (Formula I) has been described. These compounds are substantive UV-absorbers. They are useful in making fabric care products and personal care products. The scope of this methodology has been demonstrated by converting water soluble organic sunscreen quaternary halides to their corresponding tosylates of Formula VI.

  描述了一种高效、简单、高产、环保的工艺，用于制造肉桂基烷基胺和/或苯甲酰胺基烷基胺的对甲苯磺酸盐季铵盐（式 I）。这些化合物具有很强的紫外线吸收能力。它们可用于制造织物护理产品和个人护理产品。 通过将水溶性有机防晒季卤化物转化为相应的式 VI 的对甲苯磺酸盐，证明了该方法的适用范围。
• QUATERNARY SALTS OF PARA-DIALKYLAMINO BENZAMIDE DERIVATIVES
  申请人：ISP Van Dyk Inc.

  公开号：EP0738138A1

  公开（公告）日：1996-10-23