(m-chlorophenyl)-trimethyllead | 500317-00-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (m-chlorophenyl)-trimethyllead
• 英文别名: (3-Chlorophenyl)(trimethyl)plumbane；(3-chlorophenyl)-trimethylplumbane
• CAS: 500317-00-0
• 化学式: C₉H₁₃ClPb
• 分子量: 363.855
• InChiKey: APPSARNLTURXFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.89
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (-)-8-Phenylmenthyl glyoxylate hydrate 、 (m-chlorophenyl)-trimethyllead 在 di-μ-chloro-bis(1,5-cyclooctadiene)dirhodium 、 水 作用下， 生成 (R)-(3-Chloro-phenyl)-hydroxy-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 、 (S)-(3-Chloro-phenyl)-hydroxy-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
  参考文献：
  名称：

  Rhodium-catalyzed reactions of arylbismuth and aryllead reagents with a chiral glyoxylate hydrate in air and water: water-promoted diastereoselectivity enhancement

  摘要：

  In the presence of a rhodium catalyst, a chiral glyoxylate hydrate reacts with arylbismuth and aryllead reagents in water and under an atmosphere of air to give the corresponding addition products in high yields. The diastereoselectivities of the reactions were dramatically improved by using water as the solvent. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)01814-2