12,15,21,24-Tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 12,15,21,24-Tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene
• 化学式: C₂₈H₂₉NO₄
• 分子量: 443.543
• InChiKey: BUWKFNOCPWFHNA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  33
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  49
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  12,15,21,24-Tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene 、 9-溴甲基蒽 在 sodium carbonate 作用下， 以 乙腈 为溶剂， 反应 20.0h， 以90%的产率得到18-(Anthracen-9-ylmethyl)-12,15,21,24-tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene
  参考文献：
  名称：

  Fluorescent studies of two new binaphthyl–azacrown–anthracene fluorophores with metal ions and chiral guests: dual fluorescent detection via binaphthyl and anthracene groups

  摘要：

  Two new binaphthyl-azacrown-anthracene fluorophores were synthesized. These new fluorescent receptors exhibited large fluorescent changes with aqueous Hg2+, Cu2+ and Zn2+. Interestingly, the fluorescent emissions from the binaphthyl and anthracene groups using different excitation wavelengths showed different patterns in the presence of metal ions. The chiral recognitions of these receptors with chiral ammonium guests were also examined. (c) 2007 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2007.02.028
• 作为产物：
  描述：

  18-benzyl-12,15,21,24-tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene 在 palladium on activated charcoal 氢气 作用下， 以 1,4-二氧六环 为溶剂， 55.0 ℃ 、344.73 kPa 条件下， 反应 96.0h， 以62%的产率得到12,15,21,24-Tetraoxa-18-azapentacyclo[23.8.0.02,11.03,8.028,33]tritriaconta-1(25),2(11),3,5,7,9,26,28,30,32-decaene
  参考文献：
  名称：

  Synthesis, rapid resolution, and determination of absolute configuration of racemic 2,2'-binaphthyldiyl crown ethers and analogs via .beta.-cyclodextrin complexation

  摘要：

  DOI：

  10.1021/jo00350a025

文献信息

• ARMSTRONG, D. W.;WARD, T. J.;CZECH, A.;CZECH, B. P.;BARTSCH, R. A., J. ORG. CHEM., 1985, 50, N 26, 5556-5559
  作者：ARMSTRONG, D. W.、WARD, T. J.、CZECH, A.、CZECH, B. P.、BARTSCH, R. A.

  DOI：——

  日期：——
• Fluorescent studies of two new binaphthyl–azacrown–anthracene fluorophores with metal ions and chiral guests: dual fluorescent detection via binaphthyl and anthracene groups
  作者：Kwang Soo Kim、Eun Jin Jun、Sook Kyung Kim、Hee Jung Choi、Jaeduk Yoo、Chang-Hee Lee、Myung Ho Hyun、Juyoung Yoon

  DOI：10.1016/j.tetlet.2007.02.028

  日期：2007.4

  Two new binaphthyl-azacrown-anthracene fluorophores were synthesized. These new fluorescent receptors exhibited large fluorescent changes with aqueous Hg2+, Cu2+ and Zn2+. Interestingly, the fluorescent emissions from the binaphthyl and anthracene groups using different excitation wavelengths showed different patterns in the presence of metal ions. The chiral recognitions of these receptors with chiral ammonium guests were also examined. (c) 2007 Published by Elsevier Ltd.
• Synthesis, rapid resolution, and determination of absolute configuration of racemic 2,2'-binaphthyldiyl crown ethers and analogs via .beta.-cyclodextrin complexation
  作者：Daniel W. Armstrong、Timothy J. Ward、Anna Czech、Bronislaw P. Czech、Richard A. Bartsch

  DOI：10.1021/jo00350a025

  日期：1985.12