1,2-bis(dihydroxypropylphosphino)ethane | 182676-07-9

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: 1,2-bis(dihydroxypropylphosphino)ethane
• 英文别名: 1,2-bis(bis(hydroxypropyl)phosphino)ethane；dhprpe；3-[2-[Bis(3-hydroxypropyl)phosphanyl]ethyl-(3-hydroxypropyl)phosphanyl]propan-1-ol
• CAS: 182676-07-9
• 化学式: C₁₄H₃₂O₄P₂
• 分子量: 326.353
• InChiKey: SLEAGYCWTPSVCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dichloro(1,5-cyclooctadiene)ruthenium(II) 、 1,2-bis(dihydroxypropylphosphino)ethane 以 乙醇 为溶剂， 以59%的产率得到trans-Ru(1,2-bis(dihydroxypropylphosphino)ethane)2Cl2
  参考文献：
  名称：

  Aqueous Coordination Chemistry of H₂: Why is Coordinated H₂ Inert to Substitution by Water in trans-Ru(P₂)₂(H₂)H⁺-type Complexes (P₂ = a Chelating Phosphine)?

  摘要：

  The reactivity of a series of trans-Ru(P-2)(2)Cl-2 complexes with H-2 was explored. The complexes reacted with H-2 via a stepwise H-2 addition/heterolysis pathway to form the trans-[Ru(P-2)(2)(H-2)H](+) dihydrogen complexes. Some of the resulting eta(2)-H-2 complexes were surprisingly inert to substitution by water, even at concentrations as high as 55 M; however, the identity of the bidentate phosphine ligand greatly influenced the lability of the coordinated eta(2)-H-2 ligand. With less electron-donating phosphine ligands, the H-2 ligand was susceptible to substitution by H2O, whereas with more electron-rich phosphine ligands, the H-2 ligand was inert to substitution by water. Density functional theory (DFT) calculations of the ligand substitution reactions showed that the Ru-H-2 and Ru-H2O complexes are very close in energy, and therefore slight changes in the donor properties of the bidentate phosphine ligand can inhibit or promote the substitution of H2O for H-2.

  DOI：

  10.1021/ic801884x

文献信息

• Precursors to Water-Soluble Dinitrogen Carriers. Synthesis of Water-Soluble Complexes of Iron(II) Containing Water-Soluble Chelating Phosphine Ligands of the Type 1,2-Bis(bis(hydroxyalkyl)phosphino)ethane
  作者：Warren K. Miller、John D. Gilbertson、Carmen Leiva-Paredes、Paul R. Bernatis、Timothy J. R. Weakley、David K. Lyon、David R. Tyler

  DOI：10.1021/ic025774q

  日期：2002.10.1

  solvents, the reaction of FeCl(2).4H(2)O with 2 equiv of DHBuPE or DHPePE gave trans-Fe(L(2))(2)Cl(2). The analogous reactions in water with DHBuPE and DHPePE gave only cis products, and the reaction of FeSO(4).7H(2)O with any of the phosphines gave only cis-Fe(L(2))(2)SO(4). These results are interpreted as follows. The trans stereochemistry of the products from the reactions of FeCl(2).4H(2)O in alcohols

  水溶性螯合膦1,2-双（双（羟烷基）膦基）乙烷（烷基=正丙基，DHPrPE;正丁基，DHBuPE;正戊基，DHPePE）与FeCl（2）.4H的反应研究了（2）O和FeSO（4）.7H（2）O作为通往水溶性络合物的途径，该络合物将结合小分子，尤其是二氮。形成的产物及其立体化学取决于溶剂，抗衡阴离子和膦上的烷基链长。在醇类溶剂中，FeCl（2）.4H（2）O与2当量的DHBuPE或DHPePE的反应得到反式Fe（L（2））（2）Cl（2）。与DHBuPE和DHPePE在水中的类似反应仅产生顺式产物，FeSO（4）.7H（2）O与任何膦的反应仅产生顺式Fe（L（2））（2）SO（4 ）。这些结果解释如下。FeCl（2）反应产物的反式立体化学。醇中的4H（2）O被认为是Fe（H（2）O）（4）Cl（2）络合物反式几何结构的结果，即被膦取代的水分子保留了起始材料。顺式-Fe（DHPrPE）（2）C
• Synthesis and Characterization of Water-Soluble 1,2-Bis(bis(hydroxyalkyl)phosphino)ethane Ligands and Their Nickel(II), Ruthenium(III), and Rhodium(I) Complexes
  作者：Gregory T. Baxley、Warren K. Miller、David K. Lyon、Brian E. Miller、Gregory F. Nieckarz、Timothy J. R. Weakley、David R. Tyler

  DOI：10.1021/ic960766t

  日期：1996.1.1

  The syntheses of the water-soluble, chelating phosphines 1,2-bis(bis(hydroxybutyl)phosphino)ethane (1, n = 3; DHBuPE) and 1,2-bis(bis(hydroxypentyl)phosphino)ethane (1, n = 4; DHPePE) are reported. These ligands (and, in general, other 1,2-bis(bis(hydroxyalkyl)phosphino)ethane ligands) can be used to impart water solubility to metal complexes. As examples of this, the [Ni(DHPrPE)(2)Cl]Cl (2), [Rh(DHPrPE)(2)][Cl]

  水溶性螯合膦1,2-双（双（羟基丁基）膦基）乙烷（1，n = 3; DHBuPE）和1,2-双（双（羟基戊基）膦基）乙烷（1，n = 4； DHPePE）。这些配体（以及通常其他的1,2-双（双（羟烷基）膦基）乙烷配体）可用于赋予金属络合物水溶性。例如，[Ni（DHPrPE）（2）Cl] Cl（2），[Rh（DHPrPE）（2）] [Cl]（3）和[Ru（DHBuPE）（2）Cl（2）合成了[] Cl [4]配合物。它们确实溶于水（> 0.5 M）。DHPrPE（1，n = 2）晶体是单斜晶，空间群P2（1）/ c，a = 9.5935（8）Å，b = 9.353（2）Å，c = 10.655（2）Å，α= 90度，β= 100.03（1）度，伽马= 90，V = 941.5（5）Å（3），R = 0.051，Z =2。[Ni（DHPrPE）（2）Cl] Cl（2）的晶体是单斜的I2空间群，a
• Synthesis and catalytic chemistry of two new water-soluble chelating phosphines. Comparison of ionic and nonionic functionalities
  作者：Gregory T. Baxley、T.J.R. Weakley、Warren K. Miller、David K. Lyon、David R. Tyler

  DOI：10.1016/s1381-1169(96)00143-4

  日期：1997.2

  Two new water-soluble chelating alkyl phosphines are described. The compounds are prepared by radical addition of allylic substrates to 1,2-bis(phosphino)ethane in methanol. Complexes with the stoichiometry of 1.5:1 diphosphine:rhodium(I) are effective in the hydrogenation of the olefins 1-hexene and crotonaldehyde. Catalyst solutions prepared with the ligand DSPrPE were found to be 3 times more active

  描述了两种新的水溶性螯合烷基膦。通过将烯丙基底物自由基加成至甲醇中的1,2-双（膦基）乙烷中来制备化合物。化学计量比为1.5：1的二膦：铑（I）的配合物在烯烃1-己烯和巴豆醛的加氢中有效。发现在相同条件下，用配体DSPrPE制备的催化剂溶液的活性比用TPPTS（三苯基膦三磺酸盐）制备的催化剂溶液高3倍。描述了两个配体的几种铑配合物，并确定了Rh 1,2-双[（二羟丙基）膦基乙烷}} 2 Cl的晶体结构。
• Water-Soluble Mo₃S₄ Clusters Bearing Hydroxypropyl Diphosphine Ligands: Synthesis, Crystal Structure, Aqueous Speciation, and Kinetics of Substitution Reactions
  作者：Manuel G. Basallote、M. Jesús Fernández-Trujillo、Jose Ángel Pino-Chamorro、Tomás F. Beltrán、Carolina Corao、Rosa Llusar、Maxim Sokolov、Cristian Vicent

  DOI：10.1021/ic300517g

  日期：2012.6.18

  ionization mass spectrometry techniques has been carried out to understand the behavior of acid–base equilibria and the kinetics of interconversion between the 1+ and the 2+ forms. Both conversion of 1+ to 2+ and its reverse process occur in a single kinetic step, so that reactions proceed at the three metal centers with statistically controlled kinetics. The values of the rate constants under different conditions

  的[沫3小号4氯3（dhprpe）3 ] +（1 +）群集阳离子已编制之间反应的Mo 3小号4氯4（PPH 3）3（溶剂）2和水溶性1,2-双（双（羟丙基）膦基）乙烷（dhprpe，L）配体。[ 1 ] 2 [Mo 6 Cl 14的晶体结构通过X射线衍射法测定，并显示出典型的不完整的立方形结构，具有封端和三个桥联的硫化物。每个金属中心周围的八面体配位是由氯和二膦配体的两个磷原子完成的。根据pH值，官能化二膦的羟基可以取代氯化物配体并与簇核心配位，从而生成具有三齿去质子化的dhprpe配体的新簇，式为[Mo 3 S 4（dhprpe-H）3 ] +（2 +）。基于停止流量的详细研究，31 P 1为了了解酸碱平衡的行为以及1 +和2 +形式之间的相互转化动力学，已经进行了1 H NMR和电喷雾电离质谱技术的研究。1 +到2 +的转化及其逆过程都在单个动力学步骤中发生，因此反应在三个金属中心
• Absorbent solutions for separating nitrogen from natural gas
  申请人：BEND RESEARCH, INC.

  公开号：EP0800852A2

  公开（公告）日：1997-10-15

  There are disclosed nitrogen-absorbing and -desorbing compositions, together with novel ligands and transition metal complexes, and methods of using the same, which are useful for the selective separation of nitrogen from other gases, especially natural gas.

  本文公开了吸氮和脱氮组合物、新型配位体和过渡金属络合物以及使用方法，它们可用于从其他气体（尤其是天然气）中选择性地分离氮气。