1-methoxy-4-[[(E)-8-[(4-methoxyphenyl)methoxy]oct-4-enoxy]methyl]benzene | 1184854-22-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-methoxy-4-[[(E)-8-[(4-methoxyphenyl)methoxy]oct-4-enoxy]methyl]benzene
• CAS: 1184854-22-5
• 化学式: C₂₄H₃₂O₄
• 分子量: 384.516
• InChiKey: LIKWDXVPBDBLFK-ONEGZZNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  28
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-(4-methoxybenzyloxy)-1-pentene 在 Grubbs catalyst first generation 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 生成 、 1-methoxy-4-[[(E)-8-[(4-methoxyphenyl)methoxy]oct-4-enoxy]methyl]benzene
  参考文献：
  名称：

  A new strategy for the stereoselective synthesis of 2,2′-bipyrrolidines

  摘要：

  A new strategy for the stereoselective synthesis of the 2,2'-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.068

文献信息

• A new strategy for the stereoselective synthesis of 2,2′-bipyrrolidines
  作者：Mary J. Gresser、Paul A. Keller、Steven M. Wales

  DOI：10.1016/j.tetlet.2009.06.068

  日期：2009.8

  A new strategy for the stereoselective synthesis of the 2,2'-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles. (C) 2009 Elsevier Ltd. All rights reserved.