3β-Methoxy-androsten-(5)-on-(16) | 5888-04-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β-Methoxy-androsten-(5)-on-(16)
• 英文别名: 3β-methoxy-androst-5-en-16-one；3β-Methoxy-androst-5-en-16-on；Androst-5-en-16-one, 3beta-methoxy-；(3S,8S,9S,10R,13R,14S)-3-methoxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthren-16-one
• CAS: 5888-04-0
• 化学式: C₂₀H₃₀O₂
• 分子量: 302.457
• InChiKey: YWQFPAUGLVZHQW-APNJTCTJSA-N

物化性质

• 熔点：
  135-136 °C
• 沸点：
  407.3±45.0 °C(Predicted)
• 密度：
  1.07±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3β-Methoxy-androsten-(5)-on-(16) 在 platinum(IV) oxide 氢气 作用下， 以 溶剂黄146 为溶剂， 生成 3β-Methoxyandrostan-16-on
  参考文献：
  名称：

  Fajkos,J.; Joska,J., Collection of Czechoslovak Chemical Communications, 1961, vol. 26, p. 1118 - 1136

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 3β-Methoxy-androsten-(5)-on-(16)
  参考文献：
  名称：

  The germplasm release of F87084, a fertile, adapted clone with multiple disease resistances

  摘要：

  F87084 is a germplasm release that has been developed by conventional breeding methods and can be traced back to very diverse germplasm sources. This clone has excellent female fertility, round-oval tubers and is well adapted to Eastern Canada. The vine maturity is slightly later than that of Kennebec, and the mean marketable yield is 78% of Kennebec. The specific gravity, boil, bake and chip scores are somewhat lower than Kennebec. F87084 is resistant to late blight, Verticillium dahliae, early blight, and the pathotypes of wart occurring in Newfoundland. F87084 has extreme resistance to PVY degrees and PVX. It is also resistant to the potato cyst nematode pathotype Ro1. Progeny analyses indicate that F87084 is duplex for the genes controlling extreme resistance to PVX as well as resistance to the potato cyst nematode (Ro1).

  DOI：

  10.1007/bf02874769

文献信息

• Huffman et al., Journal of Biological Chemistry, 1956, vol. 222, p. 447,450
  作者：Huffman et al.

  DOI：——

  日期：——
• Fajkos,J.; Joska,J., Collection of Czechoslovak Chemical Communications, 1961, vol. 26, p. 1118 - 1136
  作者：Fajkos,J.、Joska,J.

  DOI：——

  日期：——
• The germplasm release of F87084, a fertile, adapted clone with multiple disease resistances
  作者：H. De Jong、K. G. Proudfoot、A. M. Murphy

  DOI：10.1007/bf02874769

  日期：2001.3

  F87084 is a germplasm release that has been developed by conventional breeding methods and can be traced back to very diverse germplasm sources. This clone has excellent female fertility, round-oval tubers and is well adapted to Eastern Canada. The vine maturity is slightly later than that of Kennebec, and the mean marketable yield is 78% of Kennebec. The specific gravity, boil, bake and chip scores are somewhat lower than Kennebec. F87084 is resistant to late blight, Verticillium dahliae, early blight, and the pathotypes of wart occurring in Newfoundland. F87084 has extreme resistance to PVY degrees and PVX. It is also resistant to the potato cyst nematode pathotype Ro1. Progeny analyses indicate that F87084 is duplex for the genes controlling extreme resistance to PVX as well as resistance to the potato cyst nematode (Ro1).