S-{3-(allyloxy)-2-[(trimethylsilyl)oxy]propyl} benzenecarbothioate | 1430238-07-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-{3-(allyloxy)-2-[(trimethylsilyl)oxy]propyl} benzenecarbothioate
• CAS: 1430238-07-5
• 化学式: C₁₆H₂₄O₃SSi
• 分子量: 324.516
• InChiKey: DFPVUDDJUGZWTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.98
• 重原子数：
  21.0
• 可旋转键数：
  9.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  S-benzoyl-(1-allyloxy-3-mercapto-2-hydroxypropane) 、 六甲基二硅氮烷 以 neat (no solvent) 为溶剂， 生成 S-{3-(allyloxy)-2-[(trimethylsilyl)oxy]propyl} benzenecarbothioate
  参考文献：
  名称：

  One-Pot Tandem Synthesis of β-Trimethylsilyloxy Thioesters from Thioacids, Epoxides, and HMDS Catalyzed by Silica Gel Under Solvent-Free Conditions

  摘要：

  A procedure for one-pot preparation of beta-trimethylsilyloxy thioesters from epoxides, thioacids, and hexamethyl disilazane (HMDS) in the presence of silica gel under solvent-free condition was developed. The desired silylated products were isolated in good to excellent yields after silica-gel column chromatography.Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.

  DOI：

  10.1080/00397911.2012.667183