[4-(Bromo-phenyl-methyl)-phenyl]-phenyl-methanone | 643001-27-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-(Bromo-phenyl-methyl)-phenyl]-phenyl-methanone
• 英文别名: [4-[Bromo(phenyl)methyl]phenyl]-phenylmethanone
• CAS: 643001-27-8
• 化学式: C₂₀H₁₅BrO
• 分子量: 351.242
• InChiKey: IWFRHFLQWJSAHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [4-(Bromo-phenyl-methyl)-phenyl]-phenyl-methanone 在 tetra(n-butyl)ammonium dichromate(VI) 作用下， 以 氯仿 为溶剂， 反应 3.0h， 以75%的产率得到1,4-联苯酰基苯
  参考文献：
  名称：

  A Facile Synthesis of 1,4-Diacylbenzenes

  摘要：

  An efficient method for the synthesis of 1,4-diacylbenzenes has been developed employing bis-tetrabutylammonium dichromate as an oxidant. By this methodology, a series of aldehydes and ketones have been synthesised under mild reaction conditions in moderate yields.

  DOI：

  10.1081/scc-120023419
• 作为产物：
  描述：

  (4-苄基苯基)(苯基)甲酮 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氯化碳 为溶剂， 以68%的产率得到[4-(Bromo-phenyl-methyl)-phenyl]-phenyl-methanone
  参考文献：
  名称：

  A Facile Synthesis of 1,4-Diacylbenzenes

  摘要：

  An efficient method for the synthesis of 1,4-diacylbenzenes has been developed employing bis-tetrabutylammonium dichromate as an oxidant. By this methodology, a series of aldehydes and ketones have been synthesised under mild reaction conditions in moderate yields.

  DOI：

  10.1081/scc-120023419

文献信息

• A Facile Synthesis of 1,4-Diacylbenzenes
  作者：Harindran Suhana、Panyencheri C. Srinivasan

  DOI：10.1081/scc-120023419

  日期：2003.9

  An efficient method for the synthesis of 1,4-diacylbenzenes has been developed employing bis-tetrabutylammonium dichromate as an oxidant. By this methodology, a series of aldehydes and ketones have been synthesised under mild reaction conditions in moderate yields.