5β-cholestanediol-(3α.5) | 26197-13-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5β-cholestanediol-(3α.5)
• 英文别名: 3α.5-Dihydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-5β-gonan；(10R)-3t.5c-Dihydroxy-10r.13c-dimethyl-17c-((R)-1.5-dimethyl-hexyl)-(8cH.9tH.14tH.)-hexadecahydro-1H-cyclopenta[a]phenanthren；5β-Cholestandiol-(3α.5)；coprostane-3α,5β-diol；(3R,5S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5-diol
• CAS: 26197-13-7
• 化学式: C₂₇H₄₈O₂
• 分子量: 404.677
• InChiKey: YGJKELZDRWFHOR-NQDJMPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5β-cholestanediol-(3α.5) 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 5β-Hydroxy-5β-cholestan-3-one
  参考文献：
  名称：

  关于类固醇和性激素。155。约3α，5-二氧-邻前列腺素和两个差向异构的3,4-二氧-胆甾烷

  摘要：

  通过胆甾醇环氧化物的催化还原，可以以部分合成的方式制备3α，5-二氧-共前列腺素，其在不对称中心5的空间排列上对应于司他啡啶和相关糖苷配基的构型。

  DOI：

  10.1002/hlca.19480310647
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 铂 作用下， 生成 5β-cholestanediol-(3α.5)
  参考文献：
  名称：

  关于类固醇和性激素。155。约3α，5-二氧-邻前列腺素和两个差向异构的3,4-二氧-胆甾烷

  摘要：

  通过胆甾醇环氧化物的催化还原，可以以部分合成的方式制备3α，5-二氧-共前列腺素，其在不对称中心5的空间排列上对应于司他啡啶和相关糖苷配基的构型。

  DOI：

  10.1002/hlca.19480310647

文献信息

• Is Emotional Intelligence an Advantage? An Exploration of the Impact of Emotional and General Intelligence on Individual Performance
  作者：Laura Thi Lam、Susan L. Kirby

  DOI：10.1080/00224540209603891

  日期：2002.2

  Emotional intelligence is an increasingly popular consulting tool. According to popular opinion and work-place testimonials, emotional intelligence increases performance and productivity; however, there has been a general lack of independent, systematic analysis substantiating that claim. The authors investigated whether emotional intelligence would account for increases in individual cognitive-based performance over and above the level attributable to traditional general intelligence. The authors measured emotional intelligence with the Multifactor Emotional Intelligence Scale (MEIS; J. D. Mayer, P. Salovey, & D. R. Caruso, 1997). As measured by the MEIS, overall emotional intelligence is a composite of the 3 distinct emotional reasoning abilities: perceiving, understanding, and regulating emotions (J. D. Mayer & P. Salovey, 1997). Although further psychometric analysis of the MEIS is warranted, the authors found that overall emotional intelligence, emotional perception, and emotional regulation uniquely explained individual cognitive-based performance over and beyond the level attributable to general intelligence.
• Bourdon,R.; Ranisteano,S., Bulletin de la Societe Chimique de France, 1960, p. 1977 - 1982
  作者：Bourdon,R.、Ranisteano,S.

  DOI：——

  日期：——
• Method Comparisons for Particulate Nitrate, Elemental Carbon, and PM_2.5 Mass in Seven U.S. Cities
  作者：Peter Babich、Mark Davey、George Allen、Petros Koutrakis

  DOI：10.1080/10473289.2000.10464152

  日期：2000.7

  Methods that measure PM2.5 mass, total particulate NO3-, and elemental carbon (EC) were evaluated in seven U.S. cities from 1997 to 1999. Sampling was performed in Bakersfield, CA; Boston, MA; Chicago, IL; Dallas, TX; Philadelphia, PA; Phoenix, AZ; and Riverside, CA. Evaluating and validating methods that measure the components of fine mass are important to the effort of establishing a speciation-monitoring network. The Harvard Impactor (HI), which measures fine particle mass, showed excellent agreement (r(2) = 0.99) With the PM,, Federal Reference Method (FRM) for 81 24-hr samples in Riverside and Bakersfield. The HI also showed good precision (4.8%) for 243 24-hr collocated samples over eight studies.The Aethalometer was employed in six of the sampling locations to measure black carbon (BC). These values were compared to EC as measured from a quartz filter using thermal analysis. For the six cities combined, the two methods were highly correlated (r(2) = 0.94; 187 24-hr samples); however, the BC values were approximately 24% less than the EC measurements consistently across all six cites. This compares well to results observed for EC/BC measurements observed in other semi-urban areas. Particulate NO3- was measured using the Harvard-EPA Annular Denuder System (HEADS). This was compared to the NO3- measured from the HI Teflon (DuPont) filter to assess NO3- artifacts. Significant NO3- losses (approximately 50% of total NO3-) were found in Riverside, Philadelphia, and Boston, while minimal artifacts were observed in the other sites. Two types of HEADS configurations were employed in five cities. One system used a Na2CO3-coated glass fiber filter, and the other type used a nylon filter to collect volatilized NO3- from the Teflon filter. The HEADS with the Na2CO3-coated filter consistently underestimated the total particulate NO3- by approximately 20% compared to the nylon HEADS.