(E)-2,4-dichlorobenzyl but-2-enoate | 1416170-25-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-2,4-dichlorobenzyl but-2-enoate
• 英文别名: (2,4-dichlorophenyl)methyl (E)-but-2-enoate
• CAS: 1416170-25-6
• 化学式: C₁₁H₁₀Cl₂O₂
• 分子量: 245.105
• InChiKey: OXRMQCCRXHYCBB-NSCUHMNNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,4-dichlorobenzyl but-3-enoate 在 basic alumina 作用下， 以 乙酸乙酯 、 Petroleum ether 为溶剂， 以94%的产率得到(E)-2,4-dichlorobenzyl but-2-enoate
  参考文献：
  名称：

  Palladium-Catalyzed Carboxylative Coupling of Benzyl Chlorides with Allyltributylstannane: Remarkable Effect of Palladium Nanoparticles

  摘要：

  Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane was successfully conducted to produce benzyl but-3-enoates in satisfactory to good yields. The carboxylative coupling reaction occurred smoothly under mild conditions in the presence of palladium nanoparticles in tetrahydrofuran.

  DOI：

  10.1021/ol303135e

文献信息

• Palladium-Catalyzed Carboxylative Coupling of Benzyl Chlorides with Allyltributylstannane: Remarkable Effect of Palladium Nanoparticles
  作者：Xiujuan Feng、Anle Sun、Sheng Zhang、Xiaoqiang Yu、Ming Bao

  DOI：10.1021/ol303135e

  日期：2013.1.4

  Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane was successfully conducted to produce benzyl but-3-enoates in satisfactory to good yields. The carboxylative coupling reaction occurred smoothly under mild conditions in the presence of palladium nanoparticles in tetrahydrofuran.