羟基(4-羟基-3-甲氧基苯基)乙醛 | 17592-23-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 羟基(4-羟基-3-甲氧基苯基)乙醛
• 英文名称: 3-methoxy-4-hydroxyphenylglycolaldehyde
• 英文别名: α-Hydroxy-3-methoxy-4-hydroxyphenylacetaldehyd；2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetaldehyde
• CAS: 17592-23-3
• 化学式: C₉H₁₀O₄
• 分子量: 182.176
• InChiKey: VISAJVAPYPFKCL-UHFFFAOYSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2912499000

反应信息

• 作为反应物：
  描述：

  羟基(4-羟基-3-甲氧基苯基)乙醛 生成 [4-[(Z)-1,2-bis(trimethylsilyloxy)prop-1-enyl]-2-methoxyphenoxy]-trimethylsilane
  参考文献：
  名称：

  KRAUS, PUPERT;SPITELLER, GERHARD, PHYTOCHEMISTRY, 29,(1990) N, C. 1653-1659

  摘要：

  DOI：
• 作为产物：
  描述：

  2,2,2-trichloro-1-(4-hydroxy-3-methoxy-phenyl)-ethanol 在 aluminium amalgam 、 potassium hydrogencarbonate 、 异丙醇 作用下， 生成 羟基(4-羟基-3-甲氧基苯基)乙醛
  参考文献：
  名称：

  Bal'on,Ya.G.; Shul'man,M.D., Journal of Organic Chemistry USSR (English Translation), 1976, vol. 12, p. 1926 - 1931

  摘要：

  DOI：

文献信息

• [EN] METHOD FOR PRODUCING ESTERS OF HOMOVANILLIC ACID<br/>[FR] PROCÉDÉ DE PRODUCTION D'ESTERS D'ACIDE HOMOVANILLIQUE
  申请人：SYMRISE AG

  公开号：WO2021219192A1

  公开（公告）日：2021-11-04

  The present invention primarily relates to a method for producing a compound of formula (I) and/or a physiologically acceptable salt thereof from vanillylmandelic acid and/or a physiologically acceptable salt thereof. The present invention further relates to the simultaneous use of one or more iodide salt(s) or hydrate(s) thereof, one or more reducing agent(s), one or more inorganic and/or organic acid(s) other than phosphonic acid, and methanol and/or a physiologically acceptable salt thereof or an alcohol of formula (II) as defined herein and/or a physiologically acceptable salt thereof for converting vanillylmandelic acid and/or a physiologically acceptable salt thereof into a compound of formula (I) and/or a physiologically acceptable salt thereof or into a compound of formula (III) as defined herein and/or a physiologically acceptable salt thereof.

  本发明主要涉及一种从香草酸和/或其生理上可接受的盐制备公式(I)化合物的方法，同时使用一种或多种碘化物盐或其水合物、一种或多种还原剂、一种或多种磷酸以外的无机和/或有机酸、甲醇和/或其生理上可接受的盐或本文所定义的公式(II)的醇和/或其生理上可接受的盐，将香草酸和/或其生理上可接受的盐转化为公式(I)化合物和/或其生理上可接受的盐，或者转化为本文所定义的公式(III)化合物和/或其生理上可接受的盐。
• NOVEL STEROID ESTERS USEFUL AGAINST SKIN DISORDERS
  申请人：ESTEE LAUDER INC.

  公开号：EP0876391B1

  公开（公告）日：2000-08-16
• GALLOYLATED PROCYANIDINS FOR INCREASING INTRACELLULAR NITRIC OXIDE PRODUCTION
  申请人：University of South Florida

  公开号：EP3764811A1

  公开（公告）日：2021-01-20
• Metabolomics-Based Identification of Disease-Causing Agents
  申请人：Skolnick Jeffrey

  公开号：US20110246081A1

  公开（公告）日：2011-10-06

  A method, computer-readable medium, and system for identifying one or more metabolites associated with a disease, comprising: comparing gene expression data from diseased cells to gene expression data from control cells in order to deduce genes that are differentially-regulated in the diseased cells relative to the control cells; based on enzyme function and pathway data for all human metabolites that utilize the genes that are differentially-regulated in the disease cells, identifying one or more metabolites whose intracellular levels are higher or lower in diseased cells than in control cells, and thereby associating the one or more metabolites with the disease.
• US5683705A
  申请人：——

  公开号：US5683705A

  公开（公告）日：1997-11-04