2'-O-Modified nucleosides, nucleotides, and oligonucleotides. These 2'-O-modified oligonucleotides are resistant to nuclease digestion and can effectively hybridize to a complementary polynucleotide.
2'-O-修饰核苷、核苷酸和寡核苷酸。这些2'-O修饰的寡核苷酸能够抵抗
核酸酶消化,能够有效地与互补的多核苷酸杂交。