2-[(2-甲基-2-丙基)氧基]-1,3-苯并噻唑 | 75866-98-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: 2-[(2-甲基-2-丙基)氧基]-1,3-苯并噻唑
• 英文名称: 2-tert-Butoxy-benzothiazole
• 英文别名: Benzothiazole, 2-(1,1-dimethylethoxy)-；2-[(2-methylpropan-2-yl)oxy]-1,3-benzothiazole
• CAS: 75866-98-7
• 化学式: C₁₁H₁₃NOS
• 分子量: 207.296
• InChiKey: AFGFKJIBWRJEAB-UHFFFAOYSA-N

物化性质

• 沸点：
  281.2±23.0 °C(Predicted)
• 密度：
  1.152±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  50.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-硝基-1,3-苯并噻唑 、 sodium t-butanolate 以 甲醇 为溶剂， 生成 2-[(2-甲基-2-丙基)氧基]-1,3-苯并噻唑
  参考文献：
  名称：

  Forlani, Luciano, Journal of the Chemical Society. Perkin transactions II, 1991, # 11, p. 1699 - 1702

  摘要：

  DOI：

文献信息

• Substituted Piperidines that Increase P53 Activity and the Uses Thereof
  申请人：Ma Yao

  公开号：US20080004287A1

  公开（公告）日：2008-01-03

  In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.

  在其多种实施形式中，本发明披露了作为HDM2蛋白抑制剂的新型化合物，制备这种化合物的方法，包括一种或多种这种化合物的药物组合物，以及利用这种化合物或药物组合物进行与HDM2蛋白或P53相关的一种或多种疾病的治疗、预防、抑制方法。
• Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis
  申请人：The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada

  公开号：US10945996B2

  公开（公告）日：2021-03-16

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本文提供了用于减少、预防和/或抑制C. perfringens孢子萌发的材料和方法，包括抑制C. perfringens萌发以减少动物坏死性肠炎（NE，也称为坏死性肠炎）的方法。本摘要旨在作为特定技术领域的扫描工具，供检索之用，并非对本发明的限制。
• Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis
  申请人：Abel-Santos Ernesto

  公开号：US20180000793A1

  公开（公告）日：2018-01-04

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US7884107B2
  申请人：——

  公开号：US7884107B2

  公开（公告）日：2011-02-08
• [EN] INHIBITING GERMINATION OF CLOSTRIDIUM PERFRINGENS SPORES TO REDUCE NECROTIC ENTERITIS<br/>[FR] INHIBITION DE LA GERMINATION DES SPORES DE CLOSTRIDIUM PERFRINGENS POUR RÉDUIRE L'ENTÉRITE NÉCROTIQUE
  申请人：ABEL-SANTOS ERNESTO

  公开号：WO2016127102A2

  公开（公告）日：2016-08-11

  Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C.perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.