N,N'-diphenyl-cyclopent-1-ene-1,2-dicarboxamide | 136893-23-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-diphenyl-cyclopent-1-ene-1,2-dicarboxamide
• 英文别名: N,N'-Diphenyl-cyclopent-1-en-1,2-dicarbamid；Cyclopent-1-en-1,2-dicarbanilid；Cyclopent-1-en-1,2-dicarbonsaeure-dianilid；1-N,2-N-diphenylcyclopentene-1,2-dicarboxamide
• CAS: 136893-23-7
• 化学式: C₁₉H₁₈N₂O₂
• 分子量: 306.364
• InChiKey: TVWKNFQBQYCKDE-UHFFFAOYSA-N

物化性质

• 沸点：
  577.0±50.0 °C(Predicted)
• 密度：
  1.302±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.74
• 重原子数：
  23.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  58.2
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  苯胺 、 alkaline earth salt of/the/ methylsulfuric acid 生成 N,N'-diphenyl-cyclopent-1-ene-1,2-dicarboxamide
  参考文献：
  名称：

  Studies in the Cyclopentane Series. I. The Synthesis of 1,2-Ureylenecyclopentane and Related Compounds

  摘要：

  DOI：

  10.1021/ja01150a023

文献信息

• Preparation of N-substituted phthalimides by the palladium-catalyzed carbonylation and coupling of o-dihalo aromatics and primary amines
  作者：Robert J. Perry、S. Richard Turner

  DOI：10.1021/jo00023a023

  日期：1991.11

  A novel method for the formation of N-substituted phthalimides is described which is based on the palladium-catalyzed carbonylation and coupling of o-dihalo aromatics and primary amines. Optimal conditions established for the reaction using o-diiodobenzene and aniline were DMAc (0.2 M), 115-degrees-C, 90 psi of CO, 3% PdCl2L2, and 2.4 equiv of DBU. This process is tolerant of a wide variety of functional groups and gives good yields of the desired products. Variables such as temperature, catalyst type and loading, CO pressure, solvent, and base were examined to optimize this reaction. The reaction of aniline with 1,2-dibromocyclopentene under similar conditions gave a variety of products.