4-[(E)-1-fluoro-2-phenylethenyl]sulfanylaniline | 1189143-88-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 4-[(E)-1-fluoro-2-phenylethenyl]sulfanylaniline
• CAS: 1189143-88-1
• 化学式: C₁₄H₁₂FNS
• 分子量: 245.32
• InChiKey: LGPQEXOWDDBBFD-GXDHUFHOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (E)-1-fluoro-1-phenylsulfonyl-styrene 、 4-氨基苯硫酚 在 1,1'-偶氮(氰基环己烷) 作用下， 以 甲苯 为溶剂， 反应 6.0h， 生成 、 4-[(E)-1-fluoro-2-phenylethenyl]sulfanylaniline
  参考文献：
  名称：

  Radical-mediated thiodesulfonylation of the vinyl sulfones: access to (α-fluoro)vinyl sulfides

  摘要：

  Radical-mediated thiodesulfonylation of the vinyl and (alpha-fluoro)vinyl sulfones, derived from aldehydes and ketones, with aryl thiols in organic or aqueous medium provided access to vinyl and (a-fluoro)vinyl sulfides. The vinyl sulfides were formed predominantly with E stereochemistry independent of the stereochemistry of the starting vinyl sulfones. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.063

文献信息

• Radical-mediated thiodesulfonylation of the vinyl sulfones: access to (α-fluoro)vinyl sulfides
  作者：Pablo R. Sacasa、Jessica Zayas、Stanislaw F. Wnuk

  DOI：10.1016/j.tetlet.2009.07.063

  日期：2009.9

  Radical-mediated thiodesulfonylation of the vinyl and (alpha-fluoro)vinyl sulfones, derived from aldehydes and ketones, with aryl thiols in organic or aqueous medium provided access to vinyl and (a-fluoro)vinyl sulfides. The vinyl sulfides were formed predominantly with E stereochemistry independent of the stereochemistry of the starting vinyl sulfones. (C) 2009 Elsevier Ltd. All rights reserved.