11-十二碳炔腈 | 15327-67-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 11-十二碳炔腈
• 英文名称: Dodecin-(11)-saeurenitril
• 英文别名: Dodec-11-ynenitrile；dodec-11-ynenitrile
• CAS: 15327-67-0
• 化学式: C₁₂H₁₉N
• 分子量: 177.29
• InChiKey: NPRMQFBFLQIAPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  23.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  11-十二碳炔腈 生成 1-(4-methoxy-phenyl)-13-morpholin-4-yl-tridec-11-yn-1-one
  参考文献：
  名称：

  Gautier,J.A. et al., Chimica Therapeutica, 1973, vol. 8, p. 14 - 21

  摘要：

  DOI：
• 作为产物：
  描述：

  11-氯-1-十一碳炔 、 氰化钠 在 sodium iodide 作用下， 以 乙醇 为溶剂， 生成 11-十二碳炔腈
  参考文献：
  名称：

  Gautier,J.A. et al., Bulletin de la Societe Chimique de France, 1967, p. 1551 - 1554

  摘要：

  DOI：

文献信息

• Templated monolayer polymerization and replication
  申请人：——

  公开号：US20040076757A1

  公开（公告）日：2004-04-22

  A self-replicating monolayer system employing polymerization of monomers or nanoparticle ensembles on a defined template provides a method for synthesis of two-dimensional single molecule polymers. Systems of self-replicating monolayers may be used as templates for the growth of inorganic colloids. A preferred embodiment is a SAM-based replication, wherein an initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition. Once the second monolayer has formed, it is polymerized in place and the two monolayers are separated to form a replicate. Both monolayers may then function as templates for monolayer assemblies. A generic self-replicating monomer unit suitable for use in one embodiment comprises a polymerizable moiety attached by methylene repeats to a recognition element and an ending unit that will not interfere with the chosen recognition chemistry. The recognition element is self-complementary, unless a set of two replicating monomers with compatible cross-linking chemistry is employed. In a two-component replication system utilizing two different kinds of recognition chemistries, the initial template undergoes replication cycles, while maintaining the two-dimensional segregation of the two types of monomers. During subsequent replications, the component domains experience little or no mixing, allowing the two-component, patterned assembly to be exponentially replicated. After replication, selective mineralization and/or electroless plating may produce a two-dimensional inorganic sheet having patterned domains within it.

  一种利用单体或纳米颗粒集合物在定义的模板上聚合的自复制单分子层系统，提供了一种合成二维单分子聚合物的方法。自复制单分子层系统可用作无机胶体生长的模板。首选实施方式是基于SAM的复制，其中初始单分子层被图案化并用作通过分子识别自组装第二个单分子层的模板。一旦第二个单分子层形成，它就在原位聚合，然后将两个单分子层分离以形成复制品。两个单分子层都可以作为单分子层组装的模板。适用于一种实施方式的通用自复制单体单元包括通过亚甲基重复连接到识别元素的可聚合基团和不会干扰所选择的识别化学反应的终端单元。识别元素是自互补的，除非采用具有兼容交联化学的两个复制单体的集合。在利用两种不同类型的识别化学反应的两组分复制系统中，初始模板经历复制周期，同时维持两种单体的二维分离。在随后的复制过程中，组分域经历很少或没有混合，允许指数级复制两个组分的图案组装。复制后，选择性矿化和/或电无镀可产生具有其中图案域的二维无机片。
• Templated Monolayer Polymerization and Replication
  申请人：Jacobson Joseph M.

  公开号：US20090326269A1

  公开（公告）日：2009-12-31

  A self-replicating monolayer system employing polymerization of monomers or nanoparticle ensembles on a defined template provides a method for synthesis of two-dimensional single molecule polymers. Systems of self-replicating monolayers are used as templates for growth of inorganic colloids. A preferred embodiment employs SAM-based replication, wherein an initial monolayer is patterned and used as a template for self-assembly of a second monolayer by molecular recognition. The second monolayer is polymerized in place and the monolayers are separated to form a replicate. Both may then function as templates for monolayer assemblies. A generic self-replicating monomer unit comprises a polymerizable moiety attached by methylene repeats to a recognition element and an ending unit that will not interfere with the chosen recognition chemistry. The recognition element is self-complementary, unless a set of two replicating monomers with compatible cross-linking chemistry is employed. In a two-component replication system utilizing two different kinds of recognition chemistries, the initial template undergoes replication cycles, while maintaining two-dimensional segregation of the two types of monomers. During subsequent replications, the component domains experience little or no mixing, allowing the two-component, patterned assembly to be exponentially replicated. After replication, selective mineralization and/or electroless plating may produce a two-dimensional inorganic sheet having patterned domains within it.

  一种利用单分子聚合物化或纳米颗粒集合在定义的模板上的自复制单分子层系统，提供了一种合成二维单分子聚合物的方法。自复制单分子层系统被用作无机胶体的生长模板。首选实施方式采用基于SAM的复制，其中初始单分子层被图案化并用作分子识别的模板，以自组装第二单分子层。第二单分子层在原位聚合，单分子层被分离以形成复制品。两者都可以作为单分子层组装的模板。一般的自复制单体单元包括一个可聚合的基团，通过亚甲基重复连接到一个识别元素和一个不会干扰所选择的识别化学反应的终端单元。识别元素是自补的，除非使用具有兼容交联化学的两个复制单体的集合。在利用两种不同的识别化学反应的两组分复制系统中，初始模板经历复制周期，同时保持两种单体的二维分离。在随后的复制过程中，组分区域经历很少或没有混合，允许两组分图案组装呈指数复制。复制后，选择性矿化和/或电化学镀层可产生具有图案域的二维无机片。
• Compagnon,P.-L. et al., Bulletin de la Societe Chimique de France, 1968, p. 4136 - 4141
  作者：Compagnon,P.-L. et al.

  DOI：——

  日期：——
• Polymerization of Diacetylenes by Hydrogen Bond Templated Adlayer Formation
  作者：David W. Mosley、Mark A. Sellmyer、Erin J. Daida、Joseph M. Jacobson

  DOI：10.1021/ja036625p

  日期：2003.9.1

  Adlayers were formed on self-assembled monolayers (SAMs) formed by alkanethiols on gold. Base SAMs exposing amide functional groups at the SAM surface were formed with 12-mercaptododecanamide. Adlayers of diacetylene-containing monomers were then formed via amide hydrogen bonding in decalin and decalin/toluene mixtures. Grazing angle FTIR, contact angle measurements, and ellipsometry suggest that these adlayer films exhibit ordering and packing similar to that of SAMs on gold. Resonance Raman spectroscopy showed that these diacetylene adlayers could be readily polymerized by exposure to UV light.
• US7311943B2
  申请人：——

  公开号：US7311943B2

  公开（公告）日：2007-12-25