N-(3-N'-morpholino-1-propyl)-4-butanesulphenyl-1,8-naphthalimide | 107107-80-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: N-(3-N'-morpholino-1-propyl)-4-butanesulphenyl-1,8-naphthalimide
• 英文别名: 6-Butylsulfinyl-2-(3-morpholin-4-ylpropyl)benzo[de]isoquinoline-1,3-dione
• CAS: 107107-80-2
• 化学式: C₂₃H₂₈N₂O₄S
• 分子量: 428.552
• InChiKey: CGUYXJWFBPDBHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  86.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  N-(3-氨丙基)吗啉 、 4-butanesulphenyl-1,8-naphthalic anhydride 以 乙醇 为溶剂， 反应 0.25h， 以70%的产率得到N-(3-N'-morpholino-1-propyl)-4-butanesulphenyl-1,8-naphthalimide
  参考文献：
  名称：

  Synthesis and fluorescence ofN-substituted-1,8-naphthalimides

  摘要：

  AbstractA number of novel N‐substituted‐1,8‐naphthalimides have been prepared and their fluorescence yields measured in water at pH 7.4. The type of substitutent and the substitution pattern on the naphthalimide nucleus produce markedly different fluorescence yields, (quantum efficiencies, ø varying from ø = 0‐0037 for N‐(3‐N'‐morpholino‐1‐propyl)‐4‐amino‐3‐methoxy‐1,8‐naphthalirnide (7) to ø = 0–77 for N‐(3‐bromopropyl)‐4‐acetamido‐1,8‐naphthalimide (31).

  DOI：

  10.1002/jhet.5570230337

文献信息

• Synthesis and fluorescence of<i>N</i>-substituted-1,8-naphthalimides
  作者：Richard W. Middleton、John Parrick、Eric D. Clarke、Peter Wardman

  DOI：10.1002/jhet.5570230337

  日期：1986.5

  AbstractA number of novel N‐substituted‐1,8‐naphthalimides have been prepared and their fluorescence yields measured in water at pH 7.4. The type of substitutent and the substitution pattern on the naphthalimide nucleus produce markedly different fluorescence yields, (quantum efficiencies, ø varying from ø = 0‐0037 for N‐(3‐N'‐morpholino‐1‐propyl)‐4‐amino‐3‐methoxy‐1,8‐naphthalirnide (7) to ø = 0–77 for N‐(3‐bromopropyl)‐4‐acetamido‐1,8‐naphthalimide (31).