N-(2-Diethylamino-ethyl)-maleinimid | 32658-59-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: N-(2-Diethylamino-ethyl)-maleinimid
• 英文别名: N-(2-diethylamino-ethyl)-maleimide；1-[2-(Diethylamino)ethyl]pyrrole-2,5-dione
• CAS: 32658-59-6
• 化学式: C₁₀H₁₆N₂O₂
• 分子量: 196.249
• InChiKey: UZROJLBLWLYSOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2-Diethylamino-ethyl)-maleinimid 、 希诺米啉 以 氯仿 为溶剂， 生成 3,3-dimethyl-7-oxo-2,3,6,7-tetrahydro-5H-oxazolo[3,2-a]pyrimidine-5-carboxylic acid 2-diethylamino-ethylamide
  参考文献：
  名称：

  Kampe,K.-D., Justus Liebigs Annalen der Chemie, 1974, p. 593 - 607

  摘要：

  DOI：

文献信息

• Modified cis-1,4-polyisoprene rubber, a process for its manufacture, a vulcanized modified cis-1,4-polyisoprene rubber composition and the use of the modified cis-1,4-polyisoprene rubber for preparing vulcanized shaped articles
  申请人：KURARAY CO., LTD.

  公开号：EP0066241A2

  公开（公告）日：1982-12-08

  Described is a modified cis-1,4-polyisoprene rubber on the basis of a solid synthetic cis-1,4-polyisoprene containing in its molecule per 100 repeating isoprene units at least 0.01 mole of a succinimide derivative of the general formula I wherein R1 is hydrogen or a covalent bond with the rubber molecule, R2 is a hydrocarbon residue having not more than 20 carbon atoms, and optionally containing an oxygen or sulfur atom in its principal chain, and A is a dihydrocarbylamino residue having not more than 20 carbon atoms, and containing at least one tertiary nitrogen atom as a hetero atom. This modified rubber exhibits excellent green strength at room temperature and flowability at elevated temperatures. In its vulcanized form it is comparable to, or better than vulcanized natural rubber in tensile strength and hardness.

  所述改性顺式-1,4-聚异戊二烯橡胶以固体合成顺式-1,4-聚异戊二烯为基础，其分子中每 100 个重复异戊二烯单元至少含有 0.01 摩尔通式 I 的琥珀酰亚胺衍生物。 其中 R1 是氢或与橡胶分子之间的共价键；R2 是碳原子数不超过 20 个的烃残基，其主链中可选择含有一个氧原子或硫原子；A 是碳原子数不超过 20 个的二氢羰基氨基残基，其杂质原子中至少含有一个叔氮原子。这种改性橡胶在室温下具有优异的生坯强度，在高温下具有良好的流动性。在硫化状态下，其拉伸强度和硬度与硫化天然橡胶相当，甚至更好。
• Amphiphilic adducts of myrcene and N-substituted maleimides as potential drug delivery agents
  作者：Mikhail S. Dzyurkevich、Kseniya N. Timofeeva、Dzhigangir A. Faizullin、Yuri F. Zuev、Ivan I. Stoikov、Vitaly V. Plemenkov

  DOI：10.1016/j.mencom.2014.06.012

  日期：2014.7

  The title drug delivery compounds with pharmacophoric moieties were synthesized, and their interaction with model biomembranes (dipalmitoylphosphatidylcholine vesicles) was examined.
• US20140255378A1
  申请人：——

  公开号：US20140255378A1

  公开（公告）日：2014-09-11
• US4446281A
  申请人：——

  公开号：US4446281A

  公开（公告）日：1984-05-01
• Kampe,K.-D., Justus Liebigs Annalen der Chemie, 1974, p. 593 - 607
  作者：Kampe,K.-D.

  DOI：——

  日期：——