5α-stigmastanone-(3)-oxime | 1079759-09-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5α-stigmastanone-(3)-oxime
• 英文别名: 5α-Stigmastanon-(3)-oxim；N-[(5S,8R,9S,10S,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-ylidene]hydroxylamine
• CAS: 1079759-09-3
• 化学式: C₂₉H₅₁NO
• 分子量: 429.73
• InChiKey: XQOGNSRIDFQYPT-KWMXJCMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5α-stigmastanone-(3)-oxime 、 乙酸酐 在 吡啶 作用下， 反应 18.0h， 生成 N-acetyl-(24R)-24-ethyl-5α-cholest-2-en-3-amine
  参考文献：
  名称：

  Convenient preparation of A-ring fused pyridines from steroidal enamides

  摘要：

  A facile strategy for the preparation of A-ring fused pyridosteroids has been accomplished in high yields by the reaction of Vilsmeier reagent (chloromethyleneiminium salt) with steroidal A-ring enamides (2- and 3-ene) under thermal conditions. The structure of 6'-chloro-5 alpha-cholest [3,2-b]pyridine was determined by X-ray analysis. (c) 2008 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.steroids.2008.04.016
• 作为产物：
  描述：

  豆甾烷醇 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 5α-stigmastanone-(3)-oxime
  参考文献：
  名称：

  Pragmatic guidelines for determining road investment priorities in developing countries

  摘要：

  In many developing countries, the determination of a ranking of investments designed to improve and extend the road system is a commonplace prerequisite of planning for the transport sector as a whole and the road sub-sector within it. A major objective of determining investment priorities is to secure the greatest efficiency in the use of resources allocated to the sector and, for this reason, any system of assigning priorities must rely upon conventional investment appraisal techniques producing quantifiable measures of worth. Exercises of this kind, in which road investments are identified and ranked, are usually undertaken to produce a road sector investment plan. The implementation of such plans is, however, often compromised because of perceived deficiencies with a methodology which places undue reliance on investment appraisal and fails to properly address the issue of public interest and sustainability. This paper attempts to produce a pragmatic set of ground rules which, while mindful of the need to promote economic efficiency, allow for other factors to be embraced in a more holistic methodology.

  DOI：

  10.1080/13504500209470118

文献信息

• Spinastanol and its Identity with Fucostanol and Stigmastanol
  作者：C. Donald Larsen

  DOI：10.1021/ja01277a037

  日期：1938.10
• SOUTH AFRICAN GEOMORPHOLOGY: CRITICAL CHOICES FOR THE FUTURE
  作者：H. R. BECKEDAHL、P. D. SUMNER、G. GARLAND

  DOI：10.1080/03736245.2002.9713765

  日期：2002.3
• Dalmer et al., Chemische Berichte, 1935, vol. 68, p. 1814,1817
  作者：Dalmer et al.

  DOI：——

  日期：——
• Kuwada; Morimoto, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1937, vol. 57, p. 246,250; dtsch. Ref. S. 62, 64
  作者：Kuwada、Morimoto

  DOI：——

  日期：——