trans-[TcO2(1,4,8,11-tetraazacyclotetradecane)]Cl | 163439-92-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: trans-[TcO2(1,4,8,11-tetraazacyclotetradecane)]Cl
• 英文别名: trans-[TcO2(cyclam)]Cl
• CAS: 163439-92-7
• 化学式: C₁₀H₂₄N₄O₂Tc*Cl
• 分子量: 366.779
• InChiKey: UIWSAPKWYDJBTR-RCUQKECRSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  sodium hexaflorophosphate 、 trans-[TcO2(1,4,8,11-tetraazacyclotetradecane)]Cl 以 乙腈 为溶剂， 生成 trans-[TcO2(1,4,8,11-tetraazacyclotetradecane)][PF6]
  参考文献：
  名称：

  Tc(IV)Cl4(PPh3)2 and Tc(III)Cl3(CH3CN)(PPh3)2 as precursors of trans dioxo technetium(V) complexes with chelating amines and tetraazamacrocycles

  摘要：

  The trans dioxo complexes [TcO2(L)](+) (L = 1,4,8,11-tetraazacyclotetradecane (cyclam), 1,4,8,11-tetraazacyclotetradecane-5-one, 1 4,8,11-tetraazacyclotetradecane-5,7-dione) have been prepared through a new alternative route involving the reaction of excess of the appropriate ligand with the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] in CH3CN solution, at room temperature. The yields of formation of the final products obtained through this new synthetic method (30-55%) are significantly higher than that found in the synthesis of the complex [TcO2(cyclam)](+) (7%) obtained through a previously reported procedure involving pertechnetate reduction by Na2S2O3 in alkaline solution and in the presence of the ligand or by substitution reaction onto the mono-oxo complex [TcOCl4](-). The new synthetic method was also efficiently applied to the synthesis of the trans dioxo complexes [TcO2(L')(2)](+) (L' = ethylenediamine, 1,3-propanediamine) and [TcO2(tad)](+) (tad = 1,5,8,12-tetraazadodecane), containing bidentate and tetradentate chelating amines, giving final yields similar to those obtained using [TcOCl4](-) as starting substrate. These results indicate that the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] are superior precursors for the synthesis, at macroscopic level, of trans dioxo Tc(V) complexes with tetraazamacrocyclic ligands as compared to [TcO4](-) and [TcOCl4](-). All the complexes have been characterized by elemental analysis, FTIR and mass spectra, and magnetic susceptibility measurements in solution.

  DOI：

  10.1016/0020-1693(94)04346-w
• 作为产物：
  描述：

  1,4,8,11-四氮杂环十四烷 、 tetrachlorobis(triphenylphosphine)technetium(IV) 、 水 以 乙腈 为溶剂， 生成 trans-[TcO2(1,4,8,11-tetraazacyclotetradecane)]Cl
  参考文献：
  名称：

  Tc(IV)Cl4(PPh3)2 and Tc(III)Cl3(CH3CN)(PPh3)2 as precursors of trans dioxo technetium(V) complexes with chelating amines and tetraazamacrocycles

  摘要：

  The trans dioxo complexes [TcO2(L)](+) (L = 1,4,8,11-tetraazacyclotetradecane (cyclam), 1,4,8,11-tetraazacyclotetradecane-5-one, 1 4,8,11-tetraazacyclotetradecane-5,7-dione) have been prepared through a new alternative route involving the reaction of excess of the appropriate ligand with the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] in CH3CN solution, at room temperature. The yields of formation of the final products obtained through this new synthetic method (30-55%) are significantly higher than that found in the synthesis of the complex [TcO2(cyclam)](+) (7%) obtained through a previously reported procedure involving pertechnetate reduction by Na2S2O3 in alkaline solution and in the presence of the ligand or by substitution reaction onto the mono-oxo complex [TcOCl4](-). The new synthetic method was also efficiently applied to the synthesis of the trans dioxo complexes [TcO2(L')(2)](+) (L' = ethylenediamine, 1,3-propanediamine) and [TcO2(tad)](+) (tad = 1,5,8,12-tetraazadodecane), containing bidentate and tetradentate chelating amines, giving final yields similar to those obtained using [TcOCl4](-) as starting substrate. These results indicate that the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] are superior precursors for the synthesis, at macroscopic level, of trans dioxo Tc(V) complexes with tetraazamacrocyclic ligands as compared to [TcO4](-) and [TcOCl4](-). All the complexes have been characterized by elemental analysis, FTIR and mass spectra, and magnetic susceptibility measurements in solution.

  DOI：

  10.1016/0020-1693(94)04346-w