2-(3-chloropyridin-2-yl)-5-methoxy-2H-pyrazole-3-carbonyl chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(3-chloropyridin-2-yl)-5-methoxy-2H-pyrazole-3-carbonyl chloride
• 英文别名: 2-(3-Chloropyridin-2-yl)-5-methoxy-2H-pyrazole-3-carbonyl chloride；2-(3-chloropyridin-2-yl)-5-methoxypyrazole-3-carbonyl chloride
• 化学式: C₁₀H₇Cl₂N₃O₂
• 分子量: 272.09
• InChiKey: AYIQSLBOWNQRCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  57
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(3-chloropyridin-2-yl)-5-methoxy-2H-pyrazole-3-carbonyl chloride 、 4-(全氟-2-丙基)苯胺 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 以51.2%的产率得到
  参考文献：
  名称：

  含有七氟异丙基的吡啶基吡唑酰胺类衍生物及其应用

  摘要：

  本发明涉及如通式(I)所示的含有七氟异丙基的吡啶基吡唑酰胺类衍生物的制备与应用，该类化合物代表一种广谱高效的杀虫杀菌剂结构类型。含有七氟异丙基的吡啶基吡唑酰胺类衍生物用作新型杀虫杀菌剂能很好地防治东方粘虫、小菜蛾、甜菜夜蛾；也很很好地用于防治黄瓜褐斑病、黄瓜细菌性角斑病、黄瓜枯萎病、黄瓜霜霉病、黄瓜白粉病、番茄细菌性斑点病、水稻纹枯病。式中R1、R2、R3的意义见说明书。

  公开号：

  CN105541794A
• 作为产物：
  描述：

  2-(3-chloro-2-pyridyl)-5-methoxypyrazole-3-carboxylic acid 在 草酰氯 作用下， 生成 2-(3-chloropyridin-2-yl)-5-methoxy-2H-pyrazole-3-carbonyl chloride
  参考文献：
  名称：

  [EN] CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES
  [FR] NOUVEAUX INSECTICIDES

  摘要：

  公开号：

  WO2009024341A8

文献信息

• [EN] PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBONYLCHLORIDE COMPOUNDS<br/>[FR] PROCÉDÉ DE PRÉPARATION DE COMPOSÉS 1H-PYRAZOLE-5-CARBONYLCHORURES N-SUBSTITUÉS
  申请人：BASF SE

  公开号：WO2013024007A1

  公开（公告）日：2013-02-21

  The present invention relates to a process for preparing an N-substi- tuted 1 H-pyrazole-5-carbonylchloride compound of the formula (I) comprising the steps of i) deprotonating a compound of the formula (II) with a base selected from lithium-organic base having a carbon or nitrogen bound lithium or with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a chlorocarbonylation by reacting it with a reagent selected from the group consisting of phosgene or a phosgene equivalent, to obtain a compound of formula (I).

  本发明涉及一种制备式(I)N-取代1H-吡唑-5-羰基氯化物的过程，包括以下步骤：i) 用选择自碳或氮与锂结合的有机锂碱或碳与镁结合的有机镁碱的碱去质子化式(II)化合物；和ii) 将步骤(i)中获得的产物经氯羰基化反应，与磷酰氯或磷酰氯等效物中选择的试剂反应，以获得式(I)化合物。
• [EN] ANILINE TYPE COMPOUNDS<br/>[FR] COMPOSÉS DE TYPE ANILINES
  申请人：BASF SE

  公开号：WO2013024008A1

  公开（公告）日：2013-02-21

  The present invention relates to compounds of the formula (I) wherein R1 and R2 independently of one another are hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C10-cycloalkyl, C3-C10-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl or together represent an aliphatic chain, or the like; R3 is halogen, cyano, C1-C8-alkyl, C1-C8- haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C8-alkenyl, C2-C8-haloalkenyl, C1-C8-alkoxy, phenyl, or the like; R4 is hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C8- cycloalkyl, C3-C8-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula (II) with a compound of the formulae (III) or (IV): where t, p, R1 R3, R3 and R4 are as defined in any of claims 1 to 6 and where A- is an equivalent of an anion having a pΚB of at least 10 (determined under standard conditions in water).

  本发明涉及以下式(I)的化合物，其中R1和R2彼此独立地为氢、C1-C10-烷基、C1-C10-卤代烷基、C3-C10-环烷基、C3-C10-卤代环烷基、C2-C10-烯基、C2-C10-卤代烯基或者一起代表一个脂肪链等；R3为卤素、氰基、C1-C8-烷基、C1-C8-卤代烷基、C3-C8-环烷基、C3-C8-卤代环烷基、C2-C8-烯基、C2-C8-卤代烯基、C1-C8-烷氧基、苯基等；R4为氢、C1-C10-烷基、C1-C10-卤代烷基、C3-C8-环烷基、C3-C8-卤代环烷基、C2-C10-烯基、C2-C10-卤代烯基、苯基等；t为0或1；p为0、1、2、3或4。本发明还涉及一种制备上述式(I)化合物的方法，包括将式(II)的化合物与式(III)或(IV)的化合物反应：其中t、p、R1、R3、R3和R4如权利要求1至6中的任一所定义，A-是至少在水中标准条件下具有至少10的pΚB值的阴离子的当量。
• [EN] ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES<br/>[FR] COMPOSÉS D'ANTHRANILAMIDE ET LEUR UTILISATION COMME PESTICIDES
  申请人：BASF SE

  公开号：WO2014128136A1

  公开（公告）日：2014-08-28

  The present invention relates to anthranilamide compounds of the formula (I),the stereoisomers, the salts, the tautomers and the N-oxides thereof, (I) wherein R1a, R1b,R1c,R1d are independently selected from the group consisting of hydrogen, halogen, C1-C8-alkyl, C1-C8-haloalkyl and the like; R2 is hydrogen, C1-C6-alkyl or the like; R3 is CHF2, OCH3, OCH2F or the like; R4 is hydrogen, halogen or C1-C4-haloalkyl; R5 is hydrogen, C1-C6 alkyl or the like; L is -CH2- or the like; Y is R7, OR7 or NR7R8; R6 is hydrogen, C1-C6-alkyl or the like; and R7, R8 are hydrogen, C1-C6-alkyl or the like. The present invention further relates to a method for combating or controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites, to a process for the preparation of a composition for treating infested or infected animals and/or for protecting animals against infestation or infection by parasites, and to a compound according to the invention for use as a medicament.

  本发明涉及公式（I）的蒽酰胺化合物，其立体异构体，盐，互变异构体和N-氧化物，其中R1a，R1b，R1c，R1d分别选自氢，卤素，C1-C8-烷基，C1-C8-卤代烷基等的组成的群；R2为氢，C1-C6-烷基或类似物；R3为CHF2，OCH3，OCH2F或类似物；R4为氢，卤素或C1-C4-卤代烷基；R5为氢，C1-C6烷基或类似物；L为-CH2-或类似物；Y为R7，OR7或NR7R8；R6为氢，C1-C6-烷基或类似物；R7，R8为氢，C1-C6-烷基或类似物。本发明还涉及一种用于 bekämpfung 或控制无脊椎动物害虫的方法，一种用于保护植物繁殖材料和/或生长的植物的方法，包括至少一种根据本发明的化合物的植物繁殖材料，一种用于治疗或保护动物免受寄生虫侵害或感染的方法，一种用于制备用于治疗受感染动物和/或保护动物免受寄生虫侵害或感染的组合物的方法，以及一种根据本发明用作药物的化合物。
• [EN] PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN COMPOSÉ N-1 H-PYRAZOLE SUBSTITUÉ-5-CARBOXYLATE ET DE SES DÉRIVÉS
  申请人：BASF SE

  公开号：WO2013076092A1

  公开（公告）日：2013-05-30

  The present invention relates to a process for preparing an N-substituted 1 H-pyrazole- 5- carboxylate compound of the formula (l-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (l-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I).

  本发明涉及一种制备式(l-A)的N-取代1 H-吡唑-5-羧酸酯化合物的过程，包括以下步骤：i) 用具有碳键镁的镁有机碱去质子化式(II)的化合物，其中变量R1、R2和r如描述和索赔中定义，并ii) 将步骤(i)中得到的产物经过羰基化反应，与选择自二氧化碳或二氧化碳等效物的试剂反应，得到式(l-A)的化合物；并且涉及进一步的转化以产生式(I)的N-取代1H-吡唑-5-羰基氯化物化合物。
• N-(氰基环丙基)苯甲酰胺类化合物及其应用
  申请人：江苏中旗作物保护股份有限公司

  公开号：CN105218517A

  公开（公告）日：2016-01-06

  本发明公开了通式I代表的邻甲氨基苯甲酰胺衍生物，其中通式I中R1代表H、卤素或-CN；R2代表C1-C3烷基或卤素；R3代表卤素、C1-C3烷基、C1-C3卤烷基、C1-C3烷氧基或C1-C3卤烷氧基；R4代表卤素；R5代表H、卤素、-CN或C1-C3卤烷基；本发明提供的新型的邻甲酰氨基苯甲酰胺类化合物，其本身对有害昆虫具有优良的防治效果，因此该化合物可用制备农业、园艺等领域的杀虫剂，具有高效、低毒、环境友好的优点。