2-acetoximino-2-phenylacetonitrile | 68272-44-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-acetoximino-2-phenylacetonitrile
• 英文别名: [(Z)-[cyano(phenyl)methylidene]amino] acetate
• CAS: 68272-44-6
• 化学式: C₁₀H₈N₂O₂
• 分子量: 188.186
• InChiKey: GTVUXSWBFZUBER-ZRDIBKRKSA-N

物化性质

• 沸点：
  287.7±23.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  62.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-acetoximino-2-phenylacetonitrile 、 L-α-aminoadipic acid α-benzhydryl ester 在 三乙胺 作用下， 反应 4.0h， 以90%的产率得到N-acetyl-L-α-aminoadipic acid benzhydryl ester
  参考文献：
  名称：

  Penicillin formation by cell-free extracts of Streptomycesclavuligerus. Behaviour of aminoadipyl-modified analogs of the natural peptide precursor δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine (ACV)

  摘要：

  DOI：

  10.1139/v84-462
• 作为产物：
  描述：

  (2Z)-(hydroxyimino)(phenyl)acetonitrile 、 乙酰氯 以 吡啶 、 苯 为溶剂， 反应 3.0h， 以3.1 g的产率得到2-acetoximino-2-phenylacetonitrile
  参考文献：
  名称：

  Penicillin formation by cell-free extracts of Streptomycesclavuligerus. Behaviour of aminoadipyl-modified analogs of the natural peptide precursor δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine (ACV)

  摘要：

  DOI：

  10.1139/v84-462

文献信息

• LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD
  申请人：IWAI Yu

  公开号：US20080087183A1

  公开（公告）日：2008-04-17

  A lithographic printing plate precursor includes an image-recording layer which is capable of being removed with at least one of printing ink and dampening water and contains a compound represented by the following formula (I), a sensitizing dye and a compound having at least one addition-polymerizable ethylenically unsaturated bond: wherein R 1 represents a monovalent substituent, R 2 , R 3 , R 4 , R 5 and R 6 each independently represents a hydrogen atom, a halogen atom or a monovalent substituent, and X − represents an anion.

  一种光刻印刷版前体包括一个图像记录层，该层能够被印刷油墨和润湿水中的至少一种去除，并含有以下式（I）所代表的化合物，一种敏化染料和至少一种含有至少一个加成聚合乙烯基不饱和键的化合物：其中R1代表一个单价取代基，R2、R3、R4、R5和R6各自独立地代表氢原子、卤素原子或单价取代基，X⁻代表一个阴离子。
• POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR
  申请人：Sugasaki Atsushi

  公开号：US20090053653A1

  公开（公告）日：2009-02-26

  A polymerizable composition comprising: a polyurethane resin synthesized by using a compound represented by the following formula (I) as one of starting materials; a photopolymerization or thermal polymerization initiator; and an addition-polymerizable compound having an ethylenically unsaturated bond: wherein X represents a tri- or higher valent atom; R 1 and R 2 each independently represent a single bond or an alkylene group optionally having a substituent, provided that R 1 and R 2 do not represent a single bond at a same time; A represents a straight chain linking group; and n is an integer of from 1 to 5.

  一种可聚合的组合物，包括：由使用以下式(I)所表示的化合物之一作为起始材料合成的聚氨酯树脂；光聚合或热聚合引发剂；以及具有乙烯基不饱和键的加成聚合化合物：其中，X代表三价或更高价原子；R1和R2各自独立地表示单键或具有取代基的烷基基团，但R1和R2不能同时表示单键；A表示直链连接基团；n为1到5的整数。
• SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO
  申请人：Myers Andrew G.

  公开号：US20120115818A1

  公开（公告）日：2012-05-10

  Efficient method for preparing the enone intermediate (VII) used in the synthesis of tetracyclines derivatives. In particular, the invention provides a synthesis which allows for substituents at positions 4 a , 5, 5 a , and 12 a of the tetracycline ring system.

  高效制备烯酮中间体(VII)，用于合成四环素衍生物的方法。特别地，本发明提供了一种合成方法，允许在四环素环系统的4a、5、5a和12a位置引入取代基。
• Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyrethane resin, an process for producing diol compound
  申请人：FUJIFILM Corporation

  公开号：EP2042532A2

  公开（公告）日：2009-04-01

  A polyurethane resin is synthesized from a compound represented by the following Formula (1), a polymerizable composition includes the polyurethane resin, a planographic printing plate precursor includes a photosensitive layer including the composition, and a method produces a diol compound that can be used as a raw material of the polyurethane resin. In Formula (1), R1 and R2 each independently represent a single bond or an alkylene group optionally having a substituent, R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl group, and A represents a divalent or higher linking group, provided that R1 and R2 are not both a single bond.

  一种聚氨酯树脂是由下式（1）表示的化合物合成的，一种可聚合组合物包括该聚氨酯树脂，一种平版印刷板前体包括包括该组合物的感光层，以及一种生产可用作聚氨酯树脂原料的二元醇化合物的方法。在式（1）中，R1 和 R2 各自独立地代表单键或任选具有取代基的亚烷基，R3 代表氢原子或烷基，R4 代表氢原子或烷基，A 代表二价或更高的连接基团，条件是 R1 和 R2 并非都是单键。
• Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyurethane resin, and process for producing diol compound
  申请人：FUJIFILM Corporation

  公开号：EP2042532B1

  公开（公告）日：2011-09-14