N,N,N',N'-tetrakis(3-aminopropyl)dodecamethylenediamine | 901792-07-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N,N',N'-tetrakis(3-aminopropyl)dodecamethylenediamine
• 英文别名: N,N,N',N'-tetrakis(3-aminopropyl)dodecane-1,12-diamine
• CAS: 901792-07-2
• 化学式: C₂₄H₅₆N₆
• 分子量: 428.749
• InChiKey: JXGAANHBGJSIPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  30
• 可旋转键数：
  25
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  111
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-chloro-4,6-bis(N-butyl-2,2,6,6-tetramethyl-4-piperidinylamino)-1,3,5-triazine 、 N,N,N',N'-tetrakis(3-aminopropyl)dodecamethylenediamine 以 1,3-二甲基-2-咪唑啉酮 为溶剂， 反应 5.0h， 生成 6-N-[3-[12-[bis[3-[[4,6-bis[butyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,3,5-triazin-2-yl]amino]propyl]amino]dodecyl-[3-[[4,6-bis[butyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]-1,3,5-triazin-2-yl]amino]propyl]amino]propyl]-2-N,4-N-dibutyl-2-N,4-N-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4,6-triamine
  参考文献：
  名称：

  EP1840127

  摘要：

  公开号：
• 作为产物：
  描述：

  N,N,N',N'-tetrakis(2-cyanoethyl)dodecamethylenediamine 在 Raney Co 氢气 作用下， 以 1,4-二氧六环 为溶剂， 170.0 ℃ 、8.0 MPa 条件下， 反应 2.0h， 生成 N,N,N',N'-tetrakis(3-aminopropyl)dodecamethylenediamine
  参考文献：
  名称：

  EP1840127

  摘要：

  公开号：

文献信息

• AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS
  申请人：Connor Eric

  公开号：US20140356316A1

  公开（公告）日：2014-12-04

  The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.

  本发明提供了交联胺聚合物，用于有效地结合和清除胆盐从胃肠道。这些胆酸结合聚合物或其药物组合物可以被用于治疗各种疾病，包括高胆固醇血症、糖尿病、瘙痒、肠易激综合征-腹泻（IBS-D）、胆酸吸收不良等。
• Polyamine Derivative and Polyol Derivative
  申请人：Mita Naruyoshi

  公开号：US20080230743A1

  公开（公告）日：2008-09-25

  A novel polyamine derivative, or polyol derivative, having a piperidylaminotriazine skeleton; salts of such compounds; a process for producing them; an organic material stabilizer comprising any of such compounds; a method of stabilizing an organic material; and a stabilized organic material. Compounds of the general formula: (1) (wherein X is N(R 4 ) or an oxygen atom; R 1 is an n-valent hydrocarbon group; R 2 is a hydrogen atom or an alkyl; R 3 is a hydrogen atom, an alkyl, an alkoxy or an acyl; R 4 is a hydrogen atom or an alkyl; and n is an integer of 3 to 16) are effective in the stabilization of an organic material against deterioration by light, heat, oxygen, ozone and electromagnetic waves, such as X-rays and γ-rays.

  一种新型的聚胺衍生物或聚醇衍生物，具有哌啶基氨基三嗪骨架；这些化合物的盐；一种生产它们的过程；包括上述任何一种化合物的有机材料稳定剂；一种稳定有机材料的方法；以及稳定的有机材料。通式（1）的化合物：（其中X是N（R4）或氧原子；R1是n价碳氢基团；R2是氢原子或烷基；R3是氢原子，烷基，烷氧基或酰基；R4是氢原子或烷基；n是3至16的整数）对于稳定有机材料免受光，热，氧，臭氧和电磁波（如X射线和γ射线）的损害非常有效。
• Polyamine derivative and polyol derivative
  申请人：BASF SE

  公开号：US08076478B2

  公开（公告）日：2011-12-13

  A novel polyamine derivative, or polyol derivative, having a piperidylaminotriazine skeleton; salts of such compounds; a process for producing them; an organic material stabilizer comprising any of such compounds; a method of stabilizing an organic material; and a stabilized organic material. Compounds of the general formula: (1) (wherein X is N(R4) or an oxygen atom; R1 is an n-valent hydrocarbon group; R2 is a hydrogen atom or an alkyl; R3 is a hydrogen atom, an alkyl, an alkoxy or an acyl; R4 is a hydrogen atom or an alkyl; and n is an integer of 3 to 16) are effective in the stabilization of an organic material against deterioration by light, heat, oxygen, ozone and electromagnetic waves, such as X-rays and γ-rays.

  一种新型的聚胺衍生物或聚醇衍生物，具有哌啶基氨基三嗪骨架；这些化合物的盐；一种生产它们的过程；包括任何这些化合物的有机材料稳定剂；一种稳定有机材料的方法；以及稳定的有机材料。一般式化合物：(1)（其中X是N（R4）或氧原子；R1是n价碳氢基团；R2是氢原子或烷基；R3是氢原子，烷基，烷氧基或酰基；R4是氢原子或烷基；n是3至16的整数）对于通过光，热，氧气，臭氧和电磁波（如X射线和γ射线）的恶化稳定有机材料有效。
• POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE
  申请人：MITA NARUYOSHI

  公开号：US20120053270A1

  公开（公告）日：2012-03-01

  A novel polyamine derivative, or polyol derivative, having a piperidylaminotriazine skeleton; salts of such compounds; a process for producing them; an organic material stabilizer comprising any of such compounds; a method of stabilizing an organic material; and a stabilized organinc material. Compounds of the general formula: (1) (wherein X is N(R 4 ) or an oxygen atom; R 1 is an n-valent hydrocarbon group; R 2 is an hydrogen atom or an alkyl; R 3 is a hydrogen atom, an alkyl, an alkoxy or an acyl; R 4 is a hydrogen atom or an alkyl; and n is an integer of 3 to 16) are effective in the stabilization of an organic material against deterioration by light, heat, oxygen, ozone and electromagnetic waves, such as X-rays and γ-rays.

  一种新型的聚胺衍生物或聚醇衍生物，具有哌啶基氨基三嗪骨架；这些化合物的盐；一种生产它们的过程；包括任何此类化合物的有机材料稳定剂；一种稳定有机材料的方法；以及一种稳定的有机材料。通式为（1）的化合物：（其中X是N（R4）或氧原子；R1是n价碳氢基团；R2是氢原子或烷基；R3是氢原子、烷基、烷氧基或酰基；R4是氢原子或烷基；n是3到16的整数）对于通过光、热、氧、臭氧和电磁波（如X射线和γ射线）恶化的有机材料的稳定化是有效的。
• Polyamine derivative
  申请人：BASF SE

  公开号：EP2484677A1

  公开（公告）日：2012-08-08

  A compound represented by general formula (1) wherein X represents N(R4), R1 is a group selected from a general formula (2-2): wherein R5 represents a m-valent hydrocarbon group, provided that a nitrogen atom or an oxygen atom may be contained in the hydrocarbon group R5, m represents an integer of from 2 to 8 and d represents an integer of from 1 to 6, R2 represents a hydrogen atom or an alkyl group having from 1 to 9 carbon atoms, R3 represents a hydrogen atom, an alkyl group having from 1 to 9 carbon atoms, an alkoxy group having from 1 to 9 carbon atoms or an acyl group having from 2 to 9 carbon atoms, R4 represents a hydrogen atom or an alkyl group having from 1 to 9 carbon atoms and n represents an integer of from 3 to 16, or its salt is suitable as stabilizer for organic material.

  通式(1)代表的化合物 其中 X 代表 N(R4)，R1 是选自通式（2-2）的基团： 其中 R5 代表 m 价烃基，条件是烃基 R5 中可能含有氮原子或氧原子，m 代表 2 至 8 的整数，d 代表 1 至 6 的整数、 R2 代表氢原子或具有 1 至 9 个碳原子的烷基，R3 代表氢原子、具有 1 至 9 个碳原子的烷基、具有 1 至 9 个碳原子的烷氧基或具有 2 至 9 个碳原子的酰基，R4 代表氢原子或具有 1 至 9 个碳原子的烷基，n 代表 3 至 16 的整数、 或其盐类可用作有机材料的稳定剂。