3,6-dimethyl-anthrone | 54159-95-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 3,6-dimethyl-anthrone
• 英文别名: 3,6-Dimethyl-anthron；3,6-dimethyl-10H-anthracen-9-one
• CAS: 54159-95-4
• 化学式: C₁₆H₁₄O
• 分子量: 222.287
• InChiKey: AEBXNZPHYYCJAF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,6-dimethyl-anthrone 在 chromium(VI) oxide 作用下， 生成 2,7-二甲基蒽醌
  参考文献：
  名称：

  ACID-CATALYZED REACTIONS OF VINYL COMPOUNDS: PART III. 2,7,9,10-TETRAMETHYLANTHRACENE FROM VINYL ACETATE AND TOLUENE

  摘要：

  不可用

  DOI：

  10.1139/v64-192
• 作为产物：
  描述：

  2,4,4'-trimethyldiphenylmethanone 生成 3,6-dimethyl-anthrone
  参考文献：
  名称：

  ACID-CATALYZED REACTIONS OF VINYL COMPOUNDS: PART III. 2,7,9,10-TETRAMETHYLANTHRACENE FROM VINYL ACETATE AND TOLUENE

  摘要：

  不可用

  DOI：

  10.1139/v64-192

文献信息

• TRIARYLMETHANE ANALOGS AND THEIR USE IN TREATING CANCERS
  申请人：Arbiser Jack L.

  公开号：US20090176745A1

  公开（公告）日：2009-07-09

  Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are triphenyl methane analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers, inflammatory, degenerative and vascular diseases, including various ocular diseases, and parasitic infections. Representative triphenyl methane analogs include triphenyl methane analogues of various dyes, hormones, sugars, peptides, oligonucleotides, amino acids, nucleotides, nucleosides, and polyols. The compounds are believed to function by inhibiting tNOX expression, the effects of ROS, and/or the production of HIF2. Thus, the compounds are novel therapeutic agents for a variety of cancers and other diseases.
• USE OF IMIPRAMINE BLUE AND ANALOGS THEREOF IN TREATING CANCERS
  申请人：Arbiser Jack L.

  公开号：US20100160296A1

  公开（公告）日：2010-06-24

  Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are triphenyl methane analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers, inflammatory, degenerative and vascular diseases, and parasitic infections. The compounds are triphenyl methane analogs of imipramine blue and analogs thereof, as defined herein. The compounds are believed to function by inhibiting tNOX expression, the effects of ROS, and/or the production of HIF2. Thus, the compounds are novel therapeutic agents for a variety of cancers and other diseases.
• US8435979B2
  申请人：——

  公开号：US8435979B2

  公开（公告）日：2013-05-07
• US9358226B2
  申请人：——

  公开号：US9358226B2

  公开（公告）日：2016-06-07
• ACID-CATALYZED REACTIONS OF VINYL COMPOUNDS: PART III. 2,7,9,10-TETRAMETHYLANTHRACENE FROM VINYL ACETATE AND TOLUENE
  作者：J. M. Pepper、Margaret Howell、B. P. Robinson

  DOI：10.1139/v64-192

  日期：1964.5.1

  not available

  不可用