3-(4-oxiranylphenyl)-3-trifluoromethyl-3H-diazirine | 876666-30-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(4-oxiranylphenyl)-3-trifluoromethyl-3H-diazirine
• 英文别名: 2-[4-[3-(Trifluoromethyl)-3H-diazirine-3-yl]phenyl]oxirane；3-[4-(oxiran-2-yl)phenyl]-3-(trifluoromethyl)diazirine
• CAS: 876666-30-7
• 化学式: C₁₀H₇F₃N₂O
• 分子量: 228.174
• InChiKey: JTAPQVIOBSBMKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  37.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  4-[3-(三氟甲基)-3H-双吖丙啶-3-基]苯甲醛 、 三甲基碘化锍 在 氢氧化钾 作用下， 以 水 、 乙腈 为溶剂， 反应 1.0h， 以52%的产率得到3-(4-oxiranylphenyl)-3-trifluoromethyl-3H-diazirine
  参考文献：
  名称：

  [EN] COSMETIC USE OF AND COSMETIC COMPOUND CONTAINING PHOTOREACTIVE COMPOUND, PHOTOREACTIVE POLYAMINE AND POLYAMINE SHEET
  [FR] UTILISATION COSMETIQUE D'UN COMPOSE COSMETIQUE CONTENANT UN COMPOSE PHOTOREACTIF, UNE POLYAMINE PHOTOREACTIVE ET FILM DE POLYAMINE

  摘要：

  本发明公开了一种可用于化妆目的的聚胺酸片的使用。公开了用于制造这种聚胺酸片的光敏聚胺酸以及用于制造这种光敏聚胺酸的原材料的光敏化合物，以及它们在化妆品目的中的使用和含有它们的化妆品化合物。公开了一种具有二氮杂环基团作为光敏基团的光敏化合物，由该光敏化合物和聚胺酸制成的光敏聚胺酸化合物，利用该光敏聚胺酸化合物的聚胺酸片以及其生产方法，以及它们在化妆品中的使用和含有它们的化妆品化合物。

  公开号：

  WO2006018729A1

文献信息

• Photoreactive Compound, Photoreactive Polyamine And Method For Producing Polyamine Sheet
  申请人：Hatanaka Yasumaru

  公开号：US20080069969A1

  公开（公告）日：2008-03-20

  Disclosed is a polyamine sheet which is usable for DNA chips or protein chips. Also disclosed are a photoreactive polyamine used for producing such a polyamine sheet, and a photoreactive compound which can be a raw material for such a photoreactive polyamine. Specifically disclosed are a photoreactive compound having a diazirine group as a photoreactive group, a photoreactive polyamine compound produced from such a photoreactive compound and a polyamine, a polyamine sheet using such a photoreactive polyamine compound, and a method for producing such a polyamine sheet.

  本发明公开了一种可用于DNA芯片或蛋白质芯片的聚胺酯片材。同时还公开了用于制备此类聚胺酯片材的光敏聚胺酯和可用作此类光敏聚胺酯原料的光敏化合物。具体公开了一种具有二氮杂环基团作为光敏反应基团的光敏化合物，由此类光敏化合物和聚胺酯制备的光敏聚胺酯化合物，使用此类光敏聚胺酯化合物的聚胺酯片材，以及制备此类聚胺酯片材的方法。
• Photoreactive compound, photoreactive polyamine and method for producing polyamine sheet
  申请人：University of Toyama

  公开号：US08043666B2

  公开（公告）日：2011-10-25

  Disclosed is a polyamine sheet which is usable for DNA chips or protein chips. Also disclosed are a photoreactive polyamine used for producing such a polyamine sheet, and a photoreactive compound which can be a raw material for such a photoreactive polyamine. Specifically disclosed are a photoreactive compound having a diazirine group as a photoreactive group, a photoreactive polyamine compound produced from such a photoreactive compound and a polyamine, a polyamine sheet using such a photoreactive polyamine compound, and a method for producing such a polyamine sheet.

  本发明涉及一种可用于DNA芯片或蛋白质芯片的多胺片材。同时还公开了用于制备这种多胺片材的光敏多胺，以及可作为这种光敏多胺原料的光敏化合物。具体公开了一种具有二氮杂环基团作为光敏反应基团的光敏化合物，由此类光敏化合物和多胺制得的光敏多胺化合物，使用此类光敏多胺化合物的多胺片材，以及制备此类多胺片材的方法。
• PHOTOREACTIVE COMPOUND, PHOTOREACTIVE POLYAMINE AND METHOD FOR PRODUCING POLYAMINE SHEET
  申请人：University of Toyama

  公开号：EP1785419A1

  公开（公告）日：2007-05-16

  Disclosed is a polyamine sheet which is usable for DNA chips or protein chips. Also disclosed are a photoreactive polyamine used for producing such a polyamine sheet, and a photoreactive compound which can be a raw material for such a photoreactive polyamine. Specifically disclosed are a photoreactive compound having a diazirine group as a photoreactive group, a photoreactive polyamine compound produced from such a photoreactive compound and a polyamine, a polyamine sheet using such a photoreactive polyamine compound, and a method for producing such a polyamine sheet.

  公开了一种可用于 DNA 芯片或蛋白质芯片的聚胺片材。还公开了一种用于生产这种聚胺片材的光活性聚胺，以及一种可作为这种光活性聚胺原料的光活性化合物。具体公开了具有重氮基团作为光活性基团的光活性化合物、由这种光活性化合物和多胺制得的光活性多胺化合物、使用这种光活性多胺化合物的多胺片材，以及生产这种多胺片材的方法。
• Hydrophilic Diazirine Polymer for One-Step Photo-Fabrication of Proteins on Polypropylene Surface
  作者：Yasumaru Hatanaka、Takenori Tomohiro、Norie Tachi、Yusuke Azuma

  DOI：10.3987/com-08-s(d)60

  日期：——

  A facile photochemical fabrication of chemical and biological functionalities on polypropylene surface has been performed by using photoactivatable polymers containing diazirine photophore. The water-soluble polymers have been synthesized from polyamine or polycarboxylic acid by coupling with aryldiazirine derivatives. Upon irradiation, the photoactivatable polymer successfully immobilized proteins such as horseradish peroxidase, lysozyme, and pepsin on the inert surface of polypropylene film in one step. This soft polymer cushion supplied a hydrophilic environment around the enzyme and enhanced the enzyme activity. Specifically, the polymer (HDA-PEI) introduced a hydrophilic spacer between diazirine and polymer main chain significantly increased the activity.
• US8043666B2
  申请人：——

  公开号：US8043666B2

  公开（公告）日：2011-10-25