7,7'-di-n-propoxy-[1,1']-binaphthalenyl-2,2'-diol | 695177-60-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 7,7'-di-n-propoxy-[1,1']-binaphthalenyl-2,2'-diol
• 英文别名: 1-(2-Hydroxy-7-propoxynaphthalen-1-yl)-7-propoxynaphthalen-2-ol；1-(2-hydroxy-7-propoxynaphthalen-1-yl)-7-propoxynaphthalen-2-ol
• CAS: 695177-60-7
• 化学式: C₂₆H₂₆O₄
• 分子量: 402.49
• InChiKey: WITABTJPSIIHRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  7,7'-di-n-propoxy-[1,1']-binaphthalenyl-2,2'-diol 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 12.0h， 以90%的产率得到2,12-di-n-propoxy-7-oxa-[5]-helicene
  参考文献：
  名称：

  A concise synthesis of functionalized 7-oxa-[5]-helicenes

  摘要：

  A practical procedure for the preparation of functionalized 7-oxa-[5]-helicenes from 2,7-dihydroxynaphthalene is described. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.02.105
• 作为产物：
  描述：

  2,7-二羟基萘 在 硫酸 、 三氯化铁 作用下， 以 水 为溶剂， 反应 76.0h， 生成 7,7'-di-n-propoxy-[1,1']-binaphthalenyl-2,2'-diol
  参考文献：
  名称：

  A concise synthesis of functionalized 7-oxa-[5]-helicenes

  摘要：

  A practical procedure for the preparation of functionalized 7-oxa-[5]-helicenes from 2,7-dihydroxynaphthalene is described. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.02.105

文献信息

• A class of readily available optically pure 7,7′-disubstituted BINAPs for asymmetric catalysis
  作者：Wei-Cheng Yuan、Lin-Feng Cun、Ai-Qiao Mi、Yao-Zhong Jiang、Liu-Zhu Gong

  DOI：10.1016/j.tet.2009.03.066

  日期：2009.5

  A class of optically pure 7,7'-disubstituted BINAPs have been prepared starting with a catalytic asymmetric oxidative Coupling reaction. A general, concise, and straightforward synthetic procedure has been established, and is suitable for all optically pure 7,7'-disubstituted BINAPs 1a-h, regardless of the substituents' structure in the 7,7'-positions. The catalytic potential of this class of ligands has been investigated in the highly enantioselective Rh-catalyzed 1,4-addition of aryl boronic acids to enones (up to 99.8% ee), and Ru-catalyzed asymmetric hydrogenation of simple aromatic ketones (up to S/C=100,000, up to 98% ee) and beta-ketoesters (up to S/C= 10,000, up to 99.8% ee), respectively. (C) 2009 Elsevier Ltd. All rights reserved.
• A concise synthesis of functionalized 7-oxa-[5]-helicenes
  作者：Jetsuda Areephong、Nopporn Ruangsupapichart、Tienthong Thongpanchang

  DOI：10.1016/j.tetlet.2004.02.105

  日期：2004.4

  A practical procedure for the preparation of functionalized 7-oxa-[5]-helicenes from 2,7-dihydroxynaphthalene is described. (C) 2004 Elsevier Ltd. All rights reserved.