6,6'-methylenebis(4-methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-exo-2-yl)phenol) | 124245-67-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6,6'-methylenebis(4-methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-exo-2-yl)phenol)
• 英文别名: 2-[[2-hydroxy-5-methyl-3-[(1S,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]phenyl]methyl]-4-methyl-6-[(1R,2S,4S)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]phenol
• CAS: 124245-67-6
• 化学式: C₃₅H₄₈O₂
• 分子量: 500.765
• InChiKey: SNEFZKLSLZCQKT-KQTKHCDVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.5
• 重原子数：
  37
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.66
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 2-isobornyl-4-methylphenol 在 montmorillonite KSF 作用下， 以 正辛烷 为溶剂， 反应 2.0h， 生成 6,6'-methylenebis(4-methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-exo-2-yl)phenol) 、 6,6'-methylenebis(4-methyl-2-(1,7,7-trimethylbicyclo[2.2.1]hept-exo-2-yl)phenol)
  参考文献：
  名称：

  Convenient Synthesis of 2,2′- and 4,4′-Methylenebisphenols with Bulky Alkyl Substituents and Evaluation of Their Antioxidant Activity

  摘要：

  The work is devoted to a convenient procedure of the synthesis of 2,2'- and 4,4'-methylenebisphenols with alkyl substituents in heterogeneous catalysis. This compounds were obtained with yields up to 87% by reflux of 2,4- or 2,6-dialkylphenols with HCHO in n-octane in the presence of KSF clay. We found that the antioxidant activity on DPPH test for two novel methylenebisphenols having isobornyl fragments was comparable with control drugs.

  DOI：

  10.1080/00397911.2011.589564

文献信息

• Convenient Synthesis of 2,2′- and 4,4′-Methylenebisphenols with Bulky Alkyl Substituents and Evaluation of Their Antioxidant Activity
  作者：Evgeny V. Buravlev、Irina Yu. Chukicheva、Mikhail F. Borisenkov、Aleksandr V. Kutchin

  DOI：10.1080/00397911.2011.589564

  日期：2012.12.15

  The work is devoted to a convenient procedure of the synthesis of 2,2'- and 4,4'-methylenebisphenols with alkyl substituents in heterogeneous catalysis. This compounds were obtained with yields up to 87% by reflux of 2,4- or 2,6-dialkylphenols with HCHO in n-octane in the presence of KSF clay. We found that the antioxidant activity on DPPH test for two novel methylenebisphenols having isobornyl fragments was comparable with control drugs.