N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethyl-acetamide | 949085-32-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethyl-acetamide
• 英文别名: N-methyl-2-methylsulfanyl-N-(pyridin-2-ylmethyl)acetamide
• CAS: 949085-32-9
• 化学式: C₁₀H₁₄N₂OS
• 分子量: 210.3
• InChiKey: LSBNXKSVCHQCOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  58.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethyl-acetamide 、 zinc(II) chloride 以 甲醇 为溶剂， 以93%的产率得到[Zn(N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethylacetamide)Cl2]
  参考文献：
  名称：

  Substituted pyridylmethylamide ligands and their zinc complexes

  摘要：

  Mononuclear zinc complexes of a family of pyridylmethylamide ligands abbreviated as HL, HLPh, HLMe3, HLPh3, and MeLsMe [HL = N-(2-pyridylmethyl)acetamide; HLPh = 2-phenyl-N-(2-pyridylmethyl)acetamide; HLMe3 = 2,'2-dimethyl-N-(2-pyridylmethyl)propionamide; HLPh3 = 2,2,2-triphenyl-N-(2-pyridylmethyl)acetamide; MeLSMe = N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethyl-acetamide] were synthesized and characterized spectroscopically and by single crystal X-ray structural analysis. The reaction of zinc(II) salts with the HL ligands yielded complexes [Zn(HL)(2)(OTf)(2)] (1), [Zn(HL)(2)(H2O)](ClO4)(2) (2), [Zn(HLPh3)(2)(H2O)](CLO4)(2) (3), [Zn(HLPh)Cl-2] (4), [Zn(HLMe3) Cl-2] (5), and [Zn(MeLSMe)Cl-2] (6). The complexes are either four-, five- or six-coordinate, encompassing a variety of geometries including tetrahedral, square-pyramidal, trigonal-bipyramidal, and octahedral. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2007.05.003

文献信息

• Substituted pyridylmethylamide ligands and their zinc complexes
  作者：Urmila Pal Chaudhuri、Laura R. Whiteaker、Arunendu Mondal、Eric L. Klein、Douglas R. Powell、Robert P. Houser

  DOI：10.1016/j.ica.2007.05.003

  日期：2007.8

  Mononuclear zinc complexes of a family of pyridylmethylamide ligands abbreviated as HL, HLPh, HLMe3, HLPh3, and MeLsMe [HL = N-(2-pyridylmethyl)acetamide; HLPh = 2-phenyl-N-(2-pyridylmethyl)acetamide; HLMe3 = 2,'2-dimethyl-N-(2-pyridylmethyl)propionamide; HLPh3 = 2,2,2-triphenyl-N-(2-pyridylmethyl)acetamide; MeLSMe = N-methyl-2-methylsulfanyl-N-pyridin-2-ylmethyl-acetamide] were synthesized and characterized spectroscopically and by single crystal X-ray structural analysis. The reaction of zinc(II) salts with the HL ligands yielded complexes [Zn(HL)(2)(OTf)(2)] (1), [Zn(HL)(2)(H2O)](ClO4)(2) (2), [Zn(HLPh3)(2)(H2O)](CLO4)(2) (3), [Zn(HLPh)Cl-2] (4), [Zn(HLMe3) Cl-2] (5), and [Zn(MeLSMe)Cl-2] (6). The complexes are either four-, five- or six-coordinate, encompassing a variety of geometries including tetrahedral, square-pyramidal, trigonal-bipyramidal, and octahedral. (c) 2007 Elsevier B.V. All rights reserved.