The invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis. The present invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quartenary cinchona alkaloid salts in asymmetric phase transfer catalysis. On certain substrates and under specific reaction conditions, the inventors have discovered that the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis surprisingly provides for a more active and efficient process as compared to mono-quarternary catalysts.
该发明涉及新型双季
铵金鸡纳
生物碱盐及其在不对称相转移催化中的应用。本发明涉及新型双季
铵金鸡纳
生物碱盐及其在不对称相转移催化中的应用。在某些底物和特定反应条件下,发明人发现与单季
铵催化剂相比,使用双季
铵金鸡纳
生物碱盐在不对称相转移催化中出人意料地提供了更活跃和高效的过程。