1-Acetoxy-xanthon | 51584-72-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1-Acetoxy-xanthon
• 英文别名: 1-Acetoxyxanthone；(9-oxoxanthen-1-yl) acetate
• CAS: 51584-72-6
• 化学式: C₁₅H₁₀O₄
• 分子量: 254.242
• InChiKey: SYBXJSWOUQBSHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-Acetoxy-xanthon 在 三氯化铝 、 硝基苯 作用下， 生成 1-hydroxy-2-acetylxanthone
  参考文献：
  名称：

  Reactions with Substituted Xanthones. III. Reactions with Hydroxy-9-xanthenones

  摘要：

  DOI：

  10.1021/ja01566a052
• 作为产物：
  描述：

  间苯二酚 在 sodium acetate 、 zinc(II) chloride 作用下， 生成 1-Acetoxy-xanthon
  参考文献：
  名称：

  Michael, American Chemical Journal, 1883, vol. 5, p. 89

  摘要：

  DOI：

文献信息

• An efficient and convenient microwave-assisted chemical synthesis of (thio)xanthones with additional in vitro and in silico characterization
  作者：Donatella Verbanac、Subhash C. Jain、Nidhi Jain、Mahesh Chand、Hana Čipčić Paljetak、Mario Matijašić、Mihaela Perić、Višnja Stepanić、Luciano Saso

  DOI：10.1016/j.bmc.2012.03.074

  日期：2012.5

  chemical scaffold for the synthesis of new drug candidates. One of the main obstacles in utilization of these compounds was related to the difficulties in their chemical synthesis. Most of the known methods require two steps, and are limited to specific reagents not applicable to a large number of starting materials. In this paper a new and improved method for chemical synthesis of xanthones is presented

  氧杂蒽酮及其硫代衍生物是一类具有多种药理和生物学活性的多效化合物。尽管这些活动主要是在实验室条件下确定的，但该类本身具有很大的潜力，可以用作有希望的化学支架，用于合成新的候选药物。利用这些化合物的主要障碍之一与它们的化学合成困难有关。大多数已知方法需要两个步骤，并且限于不适用于大量起始材料的特定试剂。本文提出了一种新的和改进的化学合成氧杂蒽酮的方法。通过应用新方法，我们已在较短的反应时间（50 s）和较高的收率（> 80％）。最后，进行了不同细菌种类的初步体外筛选和细胞毒性评估，以及计算机活性评估。获得的结果证实了这类分子的潜在药理学用途。
• Synthesis and pharmacological activities of xanthone derivatives as α-glucosidase inhibitors
  作者：Yan Liu、Lan Zou、Lin Ma、Wen-Hua Chen、Bo Wang、Zun-Le Xu

  DOI：10.1016/j.bmc.2006.04.014

  日期：2006.8

  Considerable interest has been attracted in xanthone and its derivatives because of their large variety of pharmacological activities. In this project, a series of hydroxylxanthones and their aectoxy and alkoxy derivatives were synthesized and evaluated as alpha-glucosidase inhibitors, aimed at clarifying the structure-activity correlation. The results indicated that these xanthone derivatives were capable of inhibiting in vitro alpha-glucosidase with moderate to good activities. Among them, polyhydroxylxanthones exhibited the highest activities and thus may be exploitable as a lead compound for the development of potent alpha-glucosidase inhibitors. (c) 2006 Elsevier Ltd. All rights reserved.
• Michael, American Chemical Journal, 1883, vol. 5, p. 89
  作者：Michael

  DOI：——

  日期：——
• PATOLIA, R.;TRIVEDI, K. N., INDIAN J. CHEM., 1983, 22, N 5, 444-447
  作者：PATOLIA, R.、TRIVEDI, K. N.

  DOI：——

  日期：——
• ADHESIVE COMPOSITION, ADHESIVE TAPE, AND METHOD FOR PROCESSING ELECTRONIC COMPONENT
  申请人：SEKISUI CHEMICAL CO., LTD.

  公开号：US20220162480A1

  公开（公告）日：2022-05-26

  The present invention aims to provide an adhesive composition that is easily separable by irradiation with light even after high-temperature processing at 300° C. or higher with an adherend fixed thereon, an adhesive tape including an adhesive layer formed of the adhesive composition, and a method for processing an electronic component. The present invention is an adhesive composition including: a reactive resin having an imide backbone and containing a double bond-containing functional group in a side chain or at an end; and a silicone compound or a fluorine compound.