tert-Butyl-{1-[(2,2-diphenyl-cyclopropyl)-methoxy-methyl]-2-phenylselanylmethyl-cyclopropoxy}-dimethyl-silane | 807329-82-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-Butyl-{1-[(2,2-diphenyl-cyclopropyl)-methoxy-methyl]-2-phenylselanylmethyl-cyclopropoxy}-dimethyl-silane
• CAS: 807329-82-4
• 化学式: C₃₃H₄₂O₂SeSi
• 分子量: 577.741
• InChiKey: DLGYYSSLKQSQSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.24
• 重原子数：
  37.0
• 可旋转键数：
  10.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  tert-Butyl-{1-[(2,2-diphenyl-cyclopropyl)-methoxy-methyl]-2-phenylselanylmethyl-cyclopropoxy}-dimethyl-silane 在 二异丁基氢化铝 作用下， 以70%的产率得到1-[(2,2-Diphenylcyclopropyl)-methoxymethyl]-2-(phenylselanylmethyl)cyclopropan-1-ol
  参考文献：
  名称：

  Lewis Acid Catalysis in Heterolysis Reactions of Glycol Ether Radicals Mimicking Diol Dehydratase-Catalyzed Reactions

  摘要：

  Zinc bromide-catalyzed heterolysis reactions of glycol ether radicals were studied by laser flash photolysis methods, which gave the binding constants and catalytic rate constants for fragmentation. The Lewis acid-catalyzed heterolysis reactions mimic a putative reaction pathway in diol dehydratase-catalyzed reactions and are potentially useful polar processes for incorporation into conventional radical chain reaction sequences.

  DOI：

  10.1021/ol0481131
• 作为产物：
  描述：

  1-(2,2-Diphenyl-cyclopropyl)-1-methoxy-propan-2-one 在 lithium aluminium tetrahydride 、 三丁基膦 、 铜 、 lithium diisopropyl amide 作用下， 生成 tert-Butyl-{1-[(2,2-diphenyl-cyclopropyl)-methoxy-methyl]-2-phenylselanylmethyl-cyclopropoxy}-dimethyl-silane
  参考文献：
  名称：

  Lewis Acid Catalysis in Heterolysis Reactions of Glycol Ether Radicals Mimicking Diol Dehydratase-Catalyzed Reactions

  摘要：

  Zinc bromide-catalyzed heterolysis reactions of glycol ether radicals were studied by laser flash photolysis methods, which gave the binding constants and catalytic rate constants for fragmentation. The Lewis acid-catalyzed heterolysis reactions mimic a putative reaction pathway in diol dehydratase-catalyzed reactions and are potentially useful polar processes for incorporation into conventional radical chain reaction sequences.

  DOI：

  10.1021/ol0481131