dicyclohexylpropylphosphine | 72144-84-4

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: dicyclohexylpropylphosphine
• 英文别名: dicyclohexylphosphino propane；dicyclohexylphosphinopropane；Dicyclohexyl(propyl)phosphane
• CAS: 72144-84-4
• 化学式: C₁₅H₂₉P
• 分子量: 240.369
• InChiKey: NYROBDNMXCGUIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  dicyclohexylpropylphosphine 、 碘甲烷 以 乙醚 为溶剂， 生成 Dicyclohexyl-methyl-propyl-phosphonium; iodide
  参考文献：
  名称：

  Payne, Nicholas C.; Stephan, Douglas W., Canadian Journal of Chemistry, 1980, vol. 58, # 1, p. 15 - 21

  摘要：

  DOI：
• 作为产物：
  描述：

  二环己基氯化膦 、 alkaline earth salt of/the/ methylsulfuric acid 以 乙醚 为溶剂， 生成 dicyclohexylpropylphosphine
  参考文献：
  名称：

  Payne, Nicholas C.; Stephan, Douglas W., Canadian Journal of Chemistry, 1980, vol. 58, # 1, p. 15 - 21

  摘要：

  DOI：

文献信息

• METHOD FOR SYNTHESIZING CYCLOHEXYL-SUBSTITUTED PHOSPHINES
  申请人：Tishkov Alexander

  公开号：US20100137643A1

  公开（公告）日：2010-06-03

  The present invention relates to a process for preparing cyclohexyl-substituted phosphines. The invention further relates to a process for preparing cyclohexyl-substituted phosphine oxides which can be used as intermediates in the preparation of cyclohexyl-substituted phosphines.

  本发明涉及一种制备环己基取代膦的方法。该发明还涉及一种制备环己基取代膦氧化物的方法，该氧化物可用作制备环己基取代膦的中间体。
• [EN] SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE IN HYDROFORMYLATION PROCESSES<br/>[FR] COMPOSÉS D'ORGANOPHOSPHINE SULFONÉE ET LEUR UTILISATION DANS LES PROCESSUS D'HYDROFORMYLATION
  申请人：DOW GLOBAL TECHNOLOGIES INC

  公开号：WO2009091669A1

  公开（公告）日：2009-07-23

  A compound comprising a sulfonated dihydrocarbyl(arylalkyl)phosphine of formula R1R2PR3-(SO3M)n, wherein the R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups, and R3 is a divalent or polyvalent arylalkylene radical such that the alkyl moiety is bonded to the phosphorus atom and the aryl moiety is bonded to the alkyl and is also substituted with one or more sulfonate groups; M is a monovalent cation, and n ranges from 1 to 3. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products. The ligand is incapable of alkyl-aryl exchange, thereby leading to reduced ligand usage and improved ligand and transition metal, e.g., rhodium, recovery and recycling.

  一种化合物，包含磺化的二烃基(芳烷基)膦，其化学式为R1R2PR3-(SO3M)n，其中R1和R2各自独立地选自烷基、芳烷基和脂环族基团，R3为二价或多价的芳烷基二价基团，使得烷基部分与磷原子相连，芳基部分与烷基相连，并且还带有一个或多个磺酸基团；M为单价阳离子，n的范围为1至3。该化合物作为配体在过渡金属-配体复合催化剂中具有应用价值，这些催化剂能够催化烯烃不饱和化合物与一氧化碳和氢气反应生成一个或多个相应的醛类产物。该配体不具备烷基-芳基交换能力，从而减少了配体的使用量，并提高了配体和过渡金属（例如铑）的回收和再循环效率。
• PROCESS FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE THROUGH COUPLING USING TRANSITION METAL CATALYST
  申请人：Komiyama Masato

  公开号：US20110313169A1

  公开（公告）日：2011-12-22

  A process for efficiently producing, through few steps either a xanthine oxidase inhibitor, which is a therapeutic agent for hyperuricemia, or an intermediate therefore. The process is a novel coupling process which comprises subjecting a compound represented by formula (1) to coupling reaction with a compound represented by formula (2) in the presence of a transition metal compound to thereby obtain a compound represented by formula (3).

  一种高效生产黄嘌呤氧化酶抑制剂或其中间体的方法，该抑制剂是治疗高尿酸血症的药物。该方法是一种新型偶联过程，包括将式（1）表示的化合物与式（2）表示的化合物在过渡金属化合物存在下进行偶联反应，从而获得式（3）表示的化合物。
• [EN] METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND<br/>[FR] PROCÉDÉ POUR LA FABRICATION D'UN COMPOSÉ ESTER DE L'ACIDE BORONIQUE
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2010110782A1

  公开（公告）日：2010-09-30

  The present invention relates to a method for manufacturing a boronic acid ester compound, characterized by reacting an aryl halide compound and a diboron ester compound in the presence of a nitrogen-containing organic base, a nickel catalyst, a phosphine compound and a solvent. According to the manufacturing method of the present invention, even if a nickel catalyst is used as the catalyst, a desired boronic acid ester compound can be obtained in a sufficiently high yield. Furthermore, even if aryl chloride or aryl bromide having relatively low price and low reactivity, was used as the aryl halide compound, a desired boronic acid ester compound can be obtained in a sufficiently high yield.

  本发明涉及一种制造硼酸酯化合物的方法，其特征在于在氮含有机碱、镍催化剂、膦化合物和溶剂的存在下，将芳基卤化物化合物和二硼酯化合物反应。根据本发明的制造方法，即使使用镍催化剂作为催化剂，也可以获得所需的硼酸酯化合物，并且收率足够高。此外，即使使用价格相对较低且反应性较低的芳基氯化物或芳基溴化物作为芳基卤化物化合物，也可以获得所需的硼酸酯化合物，并且收率足够高。
• METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND
  申请人：Miki Takashi

  公开号：US20120123122A1

  公开（公告）日：2012-05-17

  The present invention relates to a method for manufacturing a boronic acid ester compound, characterized by reacting an aryl halide compound and a diboron ester compound in the presence of a nitrogen-containing organic base, a nickel catalyst, a phosphine compound and a solvent. According to the manufacturing method of the present invention, even if a nickel catalyst is used as the catalyst, a desired boronic acid ester compound can be obtained in a sufficiently high yield. Furthermore, even if aryl chloride or aryl bromide having relatively low price and low reactivity, was used as the aryl halide compound, a desired boronic acid ester compound can be obtained in a sufficiently high yield.

  本发明涉及一种制备硼酸酯化合物的方法，其特征在于在氮含有机碱、镍催化剂、膦化合物和溶剂的存在下，将芳基卤化物化合物和二硼酯化合物反应。根据本发明的制造方法，即使使用镍催化剂作为催化剂，也可以获得所需的硼酸酯化合物，产率足够高。此外，即使使用价格较低且反应性较低的芳基氯化物或芳基溴化物作为芳基卤化物化合物，也可以获得所需的硼酸酯化合物，产率足够高。