2-methylamino-2-[N-methyl-N-(6-chloro-3-pyridylmethyl)amino]-1-nitroethylene | 120738-59-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-methylamino-2-[N-methyl-N-(6-chloro-3-pyridylmethyl)amino]-1-nitroethylene
• 英文别名: 1-[N-(6-chloro-3-pyridylmethyl)-N-methylamino]-1-methylamino-2-nitroethylene；1-N'-[(6-chloropyridin-3-yl)methyl]-1-N,1-N'-dimethyl-2-nitroethene-1,1-diamine
• CAS: 120738-59-2
• 化学式: C₁₀H₁₃ClN₄O₂
• 分子量: 256.692
• InChiKey: NXFSILLOHOWXSD-UHFFFAOYSA-N

物化性质

• 沸点：
  406.3±45.0 °C(Predicted)
• 密度：
  1.288±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  74
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  烯丙醇 、 丙烯醛 、 2-methylamino-2-[N-methyl-N-(6-chloro-3-pyridylmethyl)amino]-1-nitroethylene 在 三氟化硼乙醚 作用下， 以22.2%的产率得到6-(allyloxy)-N-((6-chloropyridin-3-yl)methyl)-N,1-dimethyl-3-nitro-1,4,5,6-tetrahydropyridin-2-amine
  参考文献：
  名称：

  Design, Synthesis, and Particular Biological Behaviors of Chain-Opening Nitromethylene Neonicotinoids with Cis Configuration

  摘要：

  On the basis of the structure of heterocyclic-fused cis configuration derivatives and chain-opening neonicotinoids, two series of novel chain-opening tetrahydropyridine analogues were designed and synthesized. The preliminary bioassay tests were determined on cowpea aphid (Aphis craccivora) and armyworm (Pseudaletia separata Walker). The results showed that some of the target compounds exhibited repellent effects, whereas others showed good insecticidal activities.

  DOI：

  10.1021/jf203068a
• 作为产物：
  描述：

  2-氯-5-氯甲基吡啶 以 乙醇 、 乙腈 为溶剂， 生成 2-methylamino-2-[N-methyl-N-(6-chloro-3-pyridylmethyl)amino]-1-nitroethylene
  参考文献：
  名称：

  Design, Synthesis, and Particular Biological Behaviors of Chain-Opening Nitromethylene Neonicotinoids with Cis Configuration

  摘要：

  On the basis of the structure of heterocyclic-fused cis configuration derivatives and chain-opening neonicotinoids, two series of novel chain-opening tetrahydropyridine analogues were designed and synthesized. The preliminary bioassay tests were determined on cowpea aphid (Aphis craccivora) and armyworm (Pseudaletia separata Walker). The results showed that some of the target compounds exhibited repellent effects, whereas others showed good insecticidal activities.

  DOI：

  10.1021/jf203068a

文献信息

• Diaminoethylene compounds
  申请人：Takeda Chemical Industries

  公开号：US05438065A1

  公开（公告）日：1995-08-01

  Diaminoethylene derivatives of the formula: ##STR1## wherein R.sup.1 is a heterocyclic group which may be substituted, R.sup.2, R.sup.3 and R.sup.4 are a hydrogen atom or a hydrocarbon group which may be substituted or R.sup.3 and R.sup.4 are combined to form a cyclic amino group together with the adjacent nitrogen atom; R.sup.5 is hydrogen atom or a hydrocarbon group or heterocyclic group which may be substituted; X is an electron attractive group; Y is a hydroxyl or substituted hydroxyl group, amino or substituted amino group or mercapto or substituted mercapto group; n is 0 or 1; or their salts, which are useful as insecticides.

  化合物的式子为：##STR1## 其中R.sup.1是一个杂环基团，可以被取代，R.sup.2，R.sup.3和R.sup.4是氢原子或烃基团，可以被取代，或者R.sup.3和R.sup.4与相邻的氮原子结合形成环状氨基团；R.sup.5是氢原子或烃基团或杂环基团，可以被取代；X是一个吸电子基团；Y是一个羟基或取代羟基基团，氨基或取代氨基基团或巯基或取代巯基基团；n为0或1；或者它们的盐，可用作杀虫剂。
• N-acylaminoacetonitrile derivatives and their use for controlling parasites
  申请人：Ducray Pierre

  公开号：US20050182127A1

  公开（公告）日：2005-08-18

  The invention relates to compounds of the general formula in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , W, X, A 1 , A 2 , a, b and c are as defined in the specification, and to any enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are particularly suitable for controlling parasites in warm-blooded animals.

  本发明涉及一般式化合物，其中R1，R2，R3，R4，R5，R6，W，X，A1，A2，a，b和c如规范中所定义，并且包括任何对映体。这些活性成分具有优越的杀虫性能。它们特别适用于控制温血动物身上的寄生虫。
• Alpha-unsaturated amines, their production and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0302389A2

  公开（公告）日：1989-02-08

  α-Unsaturated amines of the formula: wherein X¹ and X² are such that one is an electron-­attracting group with the other being a hydrogen atom or an electron-attracting group; R¹ is a group attached through a nitrogen atom; R² is a hydrogen atom or a group attached through a carbon, nitrogen or oxygen atom; n is an integer equal to 0, 1 or 2; A is a heterocyclic group or a cyclic hydrocarbon group, and salts thereof and their agrochemical use as insecticidal and/or miticidal agents are described.

  式中α-不饱和胺： 式中：X¹和X²一个是引电子基团，另一个是氢原子或引电子基团；R¹是通过氮原子连接的基团；R²是氢原子或通过碳原子、氮原子或氧原子连接的基团；n是等于0、1或2的整数；A是杂环基团或环烃基团；描述了其盐类及其作为杀虫剂和/或杀螨剂的农用化学品用途。
• Production of alpha-unsaturated amines
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0381130A2

  公开（公告）日：1990-08-08

  Methods for the production of 1,1,1,-trihalogeno-2-nitroethanes from 1,1-dihalogenoethylene by using nitric acid or its salt and hydrogen chloride or hydrogen bromide or its salt, and for the production of alpha-unsaturated amines from the 1,1,1-trihalogeno-2-­nitroethanes which are useful as insecticides.

  利用硝酸或其盐和氯化氢或溴化氢或其盐从 1，1-二卤乙烯生产 1，1，1，-三卤-2-硝基乙烷的方法，以及利用 1，1，1-三卤-2-硝基乙烷生产可用作杀虫剂的 α-不饱和胺的方法。
• Hydrazine compounds or their salts, processes for producing them and pesticides containing them
  申请人：ISHIHARA SANGYO KAISHA, LTD.

  公开号：EP0483647A1

  公开（公告）日：1992-05-06

  A hydrazine compound of the formula (I) or its salt: wherein A is a benzofuranyl group which may be substituted, a quinolinyl group which may be substituted, a benzothienyl group which may be substituted, a benzothiazolyl group which may be substituted, a thienothienyl group which may be substituted, a dihydrothienothienyl group which may be substituted, a dihydrocyclopentathienyl group which may substituted, a tetrahydrobenzothienyl group-which may be substituted, an indanyl group which may be substituted, or a hexahydroindanyl group which may be substituted, W is a hydrogen atom, a cyano group, -COCOOR', -S-N(R'')COOR' or -CH₂OCOR', wherein each of R' and R'' which are independent from each other, is an alkyl group or a cycloalkyl group, R is a halogen atom, an alkyl group which may be substituted by a halogen atom, an alkoxy group which may substituted by a halogen atom, an alkylthio group which may be substituted by a halogen atom, or a nitro group, n is an integer of from 0 to 5, provided that when n is 2 or more, the plurality of R may be the same or different.

  式 (I) 的肼化合物或其盐： 其中 A 是一个可被取代的苯并呋喃基、一个可被取代的喹啉基、一个可被取代的苯并噻吩基、一个可被取代的苯并噻唑基、一个可被取代的噻吩基、一个可被取代的二氢噻吩基、一个可被取代的二氢环噻吩基、一个可被取代的四氢苯并噻吩基、可被取代的二氢噻吩基、可被取代的二氢环戊噻吩基、可被取代的四氢苯并噻吩基、可被取代的茚基或可被取代的六氢茚基、W 是氢原子、氰基、-COCOOR'、-S-N(R'')COOR'或-CH₂OCOR'，其中 R'和 R''各自独立，是烷基或环烷基，R 是卤素原子、可被卤素原子取代的烷基、可被卤素原子取代的烷氧基、可被卤素原子取代的烷硫基或硝基，n 为 0 至 5 的整数，但当 n 为 2 或 2 以上时，多个 R 可以相同或不同。