Butyl 4-phenylsulfanylbutanoate | 29193-75-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: Butyl 4-phenylsulfanylbutanoate
• 英文别名: butyl 4-phenylsulfanylbutanoate
• CAS: 29193-75-7
• 化学式: C₁₄H₂₀O₂S
• mdl: MFCD23146850
• 分子量: 252.378
• InChiKey: YXTLHLQGVXZAKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Butyl 4-phenylsulfanylbutanoate 在 磺酰氯 作用下， 生成 Butyl 4-(4-chlorophenyl)sulfanylbutanoate
  参考文献：
  名称：

  Kukalenko,S.S., Journal of Organic Chemistry USSR (English Translation), 1970, vol. 6, p. 682 - 685

  摘要：

  DOI：
• 作为产物：
  描述：

  sodium thiophenolate 在 硫酸 作用下， 生成 Butyl 4-phenylsulfanylbutanoate
  参考文献：
  名称：

  Kukalenko,S.S., Journal of Organic Chemistry USSR (English Translation), 1970, vol. 6, p. 682 - 685

  摘要：

  DOI：

文献信息

• Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury
  申请人：Day Billy W.

  公开号：US10160705B2

  公开（公告）日：2018-12-25

  Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.

  本研究提供了抑制组蛋白脱乙酰酶活性的化合物和组合物，这些化合物和组合物能扩大肾脏祖细胞群，改善受损肾脏的肾功能。还提供了使用这些化合物和组合物的方法。
• Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury
  申请人：University of Pittsburgh - Of the Commonwealth System of Higher Education

  公开号：US20180312455A1

  公开（公告）日：2018-11-01

  Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.
• Methods of Treatment of Kidney Injury Associated with Infection or Trauma
  申请人：University of Pittsburgh - Of the Commonwealth System of Higher Education

  公开号：US20220226266A1

  公开（公告）日：2022-07-21

  Provided herein is a method of treating kidney injury associated with trauma or infection, such as in sepsis-associated acute kidney injury.
• [EN] METHODS OF TREATMENT OF KIDNEY INJURY ASSOCIATED WITH INFECTION OR TRAUMA<br/>[FR] PROCÉDÉS DE TRAITEMENT D'UNE LÉSION RÉNALE ASSOCIÉE À UNE INFECTION OU UN TRAUMATISME
  申请人：UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION

  公开号：WO2020240524A2

  公开（公告）日：2020-12-03

  Provided herein is a method of treating kidney injury associated with trauma or infection, such as in sepsis-associated acute kidney injury.