12α-hydroxy-3-oxo-23,24-dinor-5β-cholanoic acid-(21)-methyl ester | 82260-01-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 12α-hydroxy-3-oxo-23,24-dinor-5β-cholanoic acid-(21)-methyl ester
• 英文别名: 12α-Hydroxy-3-oxo-20α_F-methyl-5β-pregnansaeure-(21)-methylester；12α-Hydroxy-3-oxo-23,24-dinor-5β-cholansaeure-(21)-methylester
• CAS: 82260-01-3
• 化学式: C₂₃H₃₆O₄
• 分子量: 376.536
• InChiKey: POZONPMTNSOWDQ-DETCFEAKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.99
• 重原子数：
  27.0
• 可旋转键数：
  2.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  63.6
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  12α-hydroxy-3-oxo-23,24-dinor-5β-cholanoic acid-(21)-methyl ester 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 3,12-dioxo-23,24-dinor-5β-cholanoic acid-(21)-methyl ester
  参考文献：
  名称：

  Double ileoileal intussusception caused by a giant polypoid mass of heterotopic pancreas in a child

  摘要：

  Heterotopic pancreatic tissue has been found in several abdominal and intrathoracic locations. In the ileum, it is a rare, usually asymptomatic, incidental finding.Conclusion A unique case of a recurrent ileoileal intussusception in an 11-year-old girl is presented caused by a giant polypoid mass composed of ectopic pancreatic tissue that remained undetected during several diagnostic tests during two previous admissions and laparoscopic abdominal exploration.

  DOI：

  10.1007/pl00008355
• 作为产物：
  描述：

  3α,12α-diacetoxy-23,24-dinor-5β-cholan-22-oic acid methyl ester 在 chromium(VI) oxide 、 盐酸 、 氢氧化钾 、 溶剂黄146 作用下， 生成 12α-hydroxy-3-oxo-23,24-dinor-5β-cholanoic acid-(21)-methyl ester
  参考文献：
  名称：

  Double ileoileal intussusception caused by a giant polypoid mass of heterotopic pancreas in a child

  摘要：

  Heterotopic pancreatic tissue has been found in several abdominal and intrathoracic locations. In the ileum, it is a rare, usually asymptomatic, incidental finding.Conclusion A unique case of a recurrent ileoileal intussusception in an 11-year-old girl is presented caused by a giant polypoid mass composed of ectopic pancreatic tissue that remained undetected during several diagnostic tests during two previous admissions and laparoscopic abdominal exploration.

  DOI：

  10.1007/pl00008355