2-fluorobenzyl-triethylphosphonium bromide | 1238861-70-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-fluorobenzyl-triethylphosphonium bromide
• CAS: 1238861-70-5
• 化学式: Br*C₁₃H₂₁FP
• 分子量: 307.186
• InChiKey: WFRIVSBDLNVQKV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.41
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  2-fluorobenzyl-triethylphosphonium bromide 在 lithium hydroxide 作用下， 以 水 为溶剂， 反应 8.6h， 生成
  参考文献：
  名称：

  An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry

  摘要：

  Photovoltaic research has become increasingly prominent as the search for alternatives to fossil fuels are actively sought. A novel process for the iterative synthesis of discrete donor/acceptor-flanked oligostilbenes, key constituents in dye-sensitized solar cells, is described. The aqueous Wittig process is high yielding, proceeds with high (E)-stereoselectivity and allows facile product purification. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.040
• 作为产物：
  描述：

  triethylphosphonium hydrochloride 、 2-氟苄醇 反应 8.0h， 生成 2-fluorobenzyl-triethylphosphonium bromide
  参考文献：
  名称：

  An iterative approach toward the synthesis of discrete oligomeric p-phenylene vinylene organic dyes employing aqueous Wittig chemistry

  摘要：

  Photovoltaic research has become increasingly prominent as the search for alternatives to fossil fuels are actively sought. A novel process for the iterative synthesis of discrete donor/acceptor-flanked oligostilbenes, key constituents in dye-sensitized solar cells, is described. The aqueous Wittig process is high yielding, proceeds with high (E)-stereoselectivity and allows facile product purification. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.040

文献信息

• Microwave-Assisted, Aqueous Wittig Reactions: Organic-Solvent- and Protecting-Group-Free Chemoselective Synthesis of Functionalized Alkenes
  作者：James McNulty、Priyabrata Das、David McLeod

  DOI：10.1002/chem.201000438

  日期：——

  Free from protection! A general, chemoselective, protecting‐group‐ and organic‐solvent‐free route to stilbenes and heterostilbenes involving the direct synthesis of triethyl benzylic and allylic phosphonium salts from the corresponding alcohols and their microwave‐assisted, aqueous Wittig reactions is described.

  不受保护！描述了一种通用的，化学选择性的，无保护基团和无有机溶剂的方法，可合成出对til苯甲醛和异对til苯甲醛，涉及从相应的醇直接合成三乙基苄基和烯丙基phospho盐及其微波辅助的Wittig水溶液反应。
• Discovery of an Acid-Promoted [3+2] Cyclodimerization of 3-Vinylindoles and the Development of a General Lewis Acid Catalyzed Process
  作者：James McNulty、David McLeod

  DOI：10.1055/s-0030-1259688

  日期：2011.3

  A novel proton-catalyzed [3+2]-type cyclodimerization of 3-vinylindoles is reported leading to fused cyclopenta[b]indoles, contrasting to the normal [4+2]-cycloaddition pathway. The development of a general, high yielding version of the reaction catalyzed by zinc bromide in toluene is described.

  据报道，一种新型质子催化的 3-乙烯基吲哚[3+2]型环二聚化反应可生成融合的环戊并[b]吲哚，这与正常的[4+2]-环加成途径截然不同。报告介绍了在溴化锌催化下在甲苯中进行的一般高产反应的发展情况。