1-Phenyl-4-phenylmethoxynaphthalene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-Phenyl-4-phenylmethoxynaphthalene-2-carboxylic acid
• 英文别名: 1-phenyl-4-phenylmethoxynaphthalene-2-carboxylic acid
• 化学式: C₂₄H₁₈O₃
• 分子量: 354.405
• InChiKey: BHFYVHWKVUULAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-Phenyl-4-phenylmethoxynaphthalene-2-carboxylic acid 在 4-二甲氨基吡啶 、 copper(l) iodide 、 二苯并-18-冠醚-6 、 1,10-菲罗啉 、 palladium on activated charcoal 、 二苯基膦叠氮化物 、 水 、 甲酸铵 、 copper diacetate 、 potassium carbonate 、 溶剂黄146 、 三乙胺 、 N,N'-二环己基碳二亚胺 、 sodium hydroxide 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 165.0h， 生成 7-(3,5-Ditert-butylphenyl)benzo[c]carbazol-5-ol
  参考文献：
  名称：

  [EN] INDOLONAPHTHOPYRANS
  [FR] INDOLONAPHTOPYRANES

  摘要：

  提供的是一种具有式（I）的骨架结构的光致变色吲哚萘吡喃化合物：其中R1和R2各自独立地具有一个立体体积A，其中R1或R2中至少有一个具有至少0.6的立体体积A，R3和R4各自独立地具有一个Hammett σρ值，并且该吲哚萘吡喃化合物具有至少-3.3的计算电子立体因子。

  公开号：

  WO2020126032A1
• 作为产物：
  描述：

  1-phenyl-2-methoxycarbonyl-4-acetoxy-naphthalene 在 盐酸 、 水 、 potassium carbonate 、 sodium hydroxide 作用下， 以 甲醇 、 水 、 N,N-二甲基甲酰胺 、 异丙醇 为溶剂， 反应 36.0h， 生成 1-Phenyl-4-phenylmethoxynaphthalene-2-carboxylic acid
  参考文献：
  名称：

  [EN] METHOD FOR PREPARING INDOLENAPHTHOPYRANS
  [FR] PROCÉDÉ DE PRÉPARATION D'INDOLENAPHTOPYRANES

  摘要：

  提供了一种合成中间体，用于制备具有式（I）核心骨架结构的光致变色吲哚萘吡喃化合物，其中m为0至4，n为0至4，R1和R2分别独立为羟基、氰基、（甲基）丙烯酸酯、氨基、卤素、取代或未取代的烷基、硼酯、硼酸、聚醚、聚酯、聚碳酸酯、聚氨酯、取代或未取代的芳基、取代或未取代的杂环芳基、取代或未取代的杂芳基、取代或未取代的烷氧基、取代或未取代的芳氧基、取代或未取代的烷硫基、取代或未取代的芳硫基、酮、醛、酯、羧酸、羧酸酯、酰胺、碳酸酯、氨基甲酸酯、脲、硅氧烷、烷氧基硅烷或聚硅氧烷；R3为取代或未取代的2-吡啶基或取代或未取代的2-喹啉基；R4为氢、取代或未取代的烷基、烷氧甲基、取代或未取代的硅基或酰基。还提供了一种制备吲哚萘酚化合物的方法，包括在催化剂存在下使式（I）的苯基萘酚化合物环化。

  公开号：

  WO2020126033A1

文献信息

• NOVEL PHENYLNAPHTHOL DERIVATIVES
  申请人：TOKUYAMA CORPORATION

  公开号：US20160130203A1

  公开（公告）日：2016-05-12

  Phenylnaphthol derivatives represented by the following general formula (1), wherein, R 1 to R 3 are hydrogen atoms, alkyl groups or aryl groups, and R 2 and R 3 may be bonded together to form an aliphatic hydrocarbon ring or a heterocyclic ring, a and b are, respectively, integers of 0 to 4, R 4 and R 5 are hydroxyl groups, alkyl groups, haloalkyl groups, cycloalkyl groups, alkoxy groups, amino groups, heterocyclic groups having a nitrogen atom as a hetero atom and are bonded together via the nitrogen atom, cyano groups, nitro groups, formyl groups, hydroxycarbonyl groups, alkylcarbonyl groups, alkoxycarbonyl groups, halogen atoms, aralkyl groups, aralkoxy groups, aryloxy groups, aryl groups, heteroaryl groups bonded together via a carbon atom in the ring, alkylthio groups, cycloalkylthio groups, arylthio groups or heteroarylthio groups, and if R 4 or R 5 are present in a plural number, the plurality of R 4 or the plurality of R 5 may be the same or different, or 2 R 4 s or 2 R 5 s may be bonded together to form an alicyclic hydrocarbon ring or a heterocyclic ring. The compounds are useful as intermediate products for the synthesis of, for example, photochromic compounds.

  以下是由下列一般式（1）表示的苯基萘酚衍生物， 其中，R1至R3为氢原子、烷基或芳基，R2和R3可以结合在一起形成脂肪烃环或杂环，a和b分别为0至4的整数，R4和R5为羟基、烷基、卤代烷基、环烷基、烷氧基、氨基、含氮原子作为杂原子的杂环基，并通过氮原子结合在一起，氰基、硝基、甲酰基、羟基羰基基、烷基羰基基、烷氧羰基基、卤素原子、芳基烷基、芳基氧基、芳基氧基、芳基、通过环中的碳原子结合在一起的杂芳基、烷硫基、环烷硫基、芳硫基或杂芳硫基，如果R4或R5以复数形式存在，则复数的R4或复数的R5可以相同或不同，或2个R4或2个R5可以结合在一起形成脂环烃环或杂环。这些化合物可用作合成光变化化合物的中间产物。
• CHROMENE COMPOUND
  申请人：Izumi Shinobu

  公开号：US20140154527A1

  公开（公告）日：2014-06-05

  A chromene compound having a short fading half period, especially, a short fading half period even at a low temperature in a general-purpose polymer solid matrix. The chromene compound is represented by the following formula ( 1 ). wherein R 1 is a hydroxyl group or the like, R 2 and R 3 are each an aryl group or the like, C* is a spiro carbon atom, a spiro ring A represented by the following formula is a saturated hydrocarbon ring having 4 to 12 ring member carbon atoms or the like, and at least one ring member carbon atom constituting the ring A is a group represented by the following formula (4), and X is a divalent group such as arylene group, wherein R 7 and R 8 are each a cycloalkyl group or the like.

  具有短的褪色半衰期的香豆素化合物，特别是在通用聚合物固体基质中，即使在低温下也具有短的褪色半衰期。该香豆素化合物由以下式子（1）表示，其中R1为羟基或类似物，R2和R3分别为芳基或类似物，C*为螺碳原子，由以下式子表示的螺环A为具有4至12个环成员碳原子或类似物的饱和碳氢环，且构成环A的至少一个环成员碳原子为以下式子（4）所表示的基团，X为二价基团，例如芳基烷基，其中R7和R8分别为环烷基或类似物。
• PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND, AND OPTICAL ARTICLE
  申请人：TOKUYAMA CORPORATION

  公开号：US20210032532A1

  公开（公告）日：2021-02-04

  The invention is a photochromic compound having an indenonaphthopyran skeleton, and the indenonaphthopyran skeleton has an alkenyl group having 10 to 30 carbon atoms, and an oligomer chain group A having 3 or more recurring units selected from a polyalkylene oxide oligomer chain group, a polyester oligomer chain group, a polysiloxane chain group and a polyester polyether oligomer chain group. The invention can provide a photochromic compound capable of expressing excellent photochromic characteristics in various cured products and capable of preventing cured products from becoming cloudy.
• Indolonaphthopyrans
  申请人：Transitions Optical, Ltd.

  公开号：US20220056039A1

  公开（公告）日：2022-02-24

  Provided is a photochromic indolenaphthopyran compound having the skeletal structure of Formula (I): wherein R 1 and R 2 each independently have a steric bulk A, wherein at least one of R 1 or R 2 has a steric bulk A of at least 0.6, R 3 and R 4 each independently have a Hammett σρ value, and wherein the indolenaphthopyran compound has a calculated electronic steric factor of at least −3.3.
• Method for Preparing Indolenaphthopyrans
  申请人：Transitions Optical, Ltd.

  公开号：US20220073533A1

  公开（公告）日：2022-03-10

  Provided is a synthetic intermediate for the preparation of photochromic indolenaphthopyran compounds having the core skeletal structure of Formula (I): wherein m is 0 to 4, n is 0 to 4, R 1 and R 2 are each independently hydroxyl, cyano, (meth)acrylate, amino, halo, substituted or unsubstituted alkyl, boronic ester, boronic acid, polyether, polyester, polycarbonate, polyurethane, substituted or unsubstituted aryl, substituted or unsubstituted heterocycloaryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryloxy, substituted or unsubstituted alkylthio, substituted or unsubstituted arylthio, ketone, aldehyde, ester, carboxylic acid, carboxylate, amide, carbonate, carbamate, urea, siloxane, alkoxysilane, or polysiloxane; R 3 is substituted or unsubstituted 2-pyridyl or substituted or unsubstituted 2-quinolyl; and R 4 is hydrogen, substituted or unsubstituted alkyl, alkoxymethyl, substituted or unsubstituted silyl, or acyl. Also provided is a process for producing an indolenaphthol compound which includes cyclizing the phenylnaphthol compound of Formula (I) in the presence of a catalyst.