Dibenzyloxycarbonyl-L-lysinamid | 55592-79-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Dibenzyloxycarbonyl-L-lysinamid
• 英文别名: N^α.N^ε-bis-benzyloxycarbonyl-L-lysine amide；N^α.N^ε-Bis-benzyloxycarbonyl-L-lysin-amid；N,N'-Bis(carbobenzyloxy)-L-lysinamide；benzyl N-[(2S)-1-amino-1-oxo-6-(phenylmethoxycarbonylamino)hexan-2-yl]carbamate
• CAS: 55592-79-5
• 化学式: C₂₂H₂₇N₃O₅
• 分子量: 413.473
• InChiKey: XAWFZEHAYVXQHS-IBGZPJMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  30
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  120
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Dibenzyloxycarbonyl-L-lysinamid 在 劳森试剂 作用下， 生成
  参考文献：
  名称：

  偶氮化合物作为基于模块肽的配体，用于不对称路易斯酸催化

  摘要：

  据报道，偶氮化物的合成及其作为对映选择性路易斯酸催化的配体的评估。配体很容易从氨基酸的手性库中制备，并在钴（II）催化的不对称杂Diels-Alder加合物的形成中表现出色。提供了由计算计算支持的观察到的对映选择性和转化率的合理性。

  DOI：

  10.1021/acs.joc.9b00732
• 作为产物：
  描述：

  N2,N6-二[(苯基甲氧基)羰基]-L-赖氨酸 4-硝基苯基酯 在 氨 作用下， 以 甲醇 为溶剂， 生成 Dibenzyloxycarbonyl-L-lysinamid
  参考文献：
  名称：

  Schnabel,E., Justus Liebigs Annalen der Chemie, 1962, vol. 659, p. 168 - 184

  摘要：

  DOI：

文献信息

• Population Exposure to Electromagnetic Fields Generated by Radio Base Stations: Evaluation of the Urban Background by Using Provisional Model and Instrumental Measurements
  作者：L. Anglesio、A. Benedetto、A. Bonino、D. Colla、F. Martire、S. Saudino Fusette、G. d'Amore

  DOI：10.1093/oxfordjournals.rpd.a006688

  日期：2001.12.1

  Electromagnetic radiation, which is used by broadcasting and mobile telephone systems to transmit information, permeates the city environment. In order to properly evaluate population exposure to electromagnetic fields, knowledge of their intensity and spectral components is necessary. In this study the results of radiofrequency field monitoring carried out in Torino, a large town located in the north-west of Italy are shown: the variation of the electromagnetic field strength is evaluated as a function of the height from the ground, the location in the urban area and the frequency, separating the contributions of the different sources (broadcasting antennas and radio base stations for mobile phones). Furthermore, the contribution of the radio base stations is theoretically evaluated, adding the emissions off all installations situated in Torino and examining the field strength maps calculated, considering the orography, for different heights. The theoretical values are also compared with those measured in the frequency range of mobile telephony emissions.

  广播和移动电话系统用来传输信息的电磁辐射渗透到城市环境中。为了正确评估人口暴露于电磁场的情况，有必要了解其强度和光谱成分。本研究显示了在都灵（位于意大利西北部的一个大城市）进行的射频场监测结果：将电磁场强度的变化作为离地高度、城市区域位置和频率的函数进行评估，并将不同来源（广播天线和移动电话无线基站）的贡献分开。此外，还对无线电基站的贡献进行了理论评估，将都灵所有设施的辐射量相加，并根据不同高度的地形计算出场强图。理论值还与移动电话发射频率范围内的测量值进行了比较。
• Evaluation of Long-term Exposure to the Magnetic Field Produced from Power Lines
  作者：G. Licitra、N. Colonna、C. Chiari

  DOI：10.1093/oxfordjournals.rpd.a006697

  日期：2001.12.1

  For some years, the Italian Regional Agencies for Environmental Protection have been engaged in the evaluation of long-term exposure to 50 Hz magnetic fields for receptors close to power lines. In this study, experiences and procedures are suggested in order to estimate long-term exposure levels in the case of magnetic induction produced contemporaneously by different power lines. In the simplest cases, the influence of a single line is evaluated by verifying the correlation factor between the variation of the current in each line and the measured magnetic induction. When the prevalence of a single line is not clear and systematic, much additional data (voltage, current, phases and geometrical configuration) have to be considered. The case of a school in Livorno near two lines, placed on the same supports, is described and a range of the most probable exposure values is given, corresponding to the phase change of the two current fluxes.

  多年来，意大利地区环境保护机构一直致力于评估靠近电源线的接收器长期暴露于 50 Hz 磁场的情况。在这项研究中，建议了经验和程序，以便估计不同电力线同时产生磁感应情况下的长期暴露水平。在最简单的情况下，通过验证每条线路中的电流变化与测量的磁感应强度之间的相关系数来评估单条线路的影响。当单条线路的流行情况不明确且系统化时，必须考虑许多附加数据（电压、电流、相位和几何配置）。描述了位于利沃诺的一所学校靠近两条线且放置在相同支撑物上的情况，并给出了最可能的暴露值的范围，对应于两个电流通量的相位变化。
• Bergmann; Zervas; Ross, Journal of Biological Chemistry, 1935, vol. 111, p. 245,251
  作者：Bergmann、Zervas、Ross

  DOI：——

  日期：——
• Azotides as Modular Peptide-Based Ligands for Asymmetric Lewis Acid Catalysis
  作者：Christian Borch Jacobsen、Daniel Steen Nielsen、Morten Meldal、Frederik Diness

  DOI：10.1021/acs.joc.9b00732

  日期：2019.6.7

  Synthesis of azotides and evaluation of these as ligands for enantioselective Lewis acid catalysis is reported. The ligands were readily prepared from the chiral pool of amino acids and perform well in the cobalt(II)-catalyzed formation of asymmetric hetero Diels–Alder adducts. A rational for the observed enantioselectivity and conversion rate supported by computational calculations is provided.

  据报道，偶氮化物的合成及其作为对映选择性路易斯酸催化的配体的评估。配体很容易从氨基酸的手性库中制备，并在钴（II）催化的不对称杂Diels-Alder加合物的形成中表现出色。提供了由计算计算支持的观察到的对映选择性和转化率的合理性。
• Schnabel,E., Justus Liebigs Annalen der Chemie, 1962, vol. 659, p. 168 - 184
  作者：Schnabel,E.

  DOI：——

  日期：——