Benzyl 1,2,2,2-tetrafluoroethyl sulfide | 130612-80-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzyl 1,2,2,2-tetrafluoroethyl sulfide
• 英文别名: 1,2,2,2-Tetrafluoroethylsulfanylmethylbenzene
• CAS: 130612-80-5
• 化学式: C₉H₈F₄S
• 分子量: 224.222
• InChiKey: XBKXWZOMGZCZCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  苄基2,2,2-三氟乙基硫醚 在 triethylamine tris(hydrogen fluoride) 作用下， 以 乙腈 为溶剂， 以25%的产率得到Benzyl 1,2,2,2-tetrafluoroethyl sulfide
  参考文献：
  名称：

  Electrolytic partial fluorination of organic compounds. 1. Regioselective anodic monofluorination of organosulfur compounds

  摘要：

  DOI：

  10.1021/jo00312a006

文献信息

• Electrolytic Partial Fluorination of Organic Compounds. 12. Selective Anodic Monofluorination of Fluoroalkyl and Alkyl Sulfides
  作者：Toshio Fuchigami、Akinori Konno、Kiyono Nakagawa、Moriyasu Shimojo

  DOI：10.1021/jo00099a023

  日期：1994.10

  Highly regioselective anodic monofluorination of various aryl and alkyl fluoroalkyl sulfides was successfully carried out, and fluorine was exclusively (aryl sulfides) or preferentially (alkyl sulfides) introduced at the position alpha to the fluoroalkyl group. Even simple alkyl phenyl sulfides devoid of an electron-withdrawing group could be anodically monofluorinated in satisfactory yields for the first time when etheral solvents were used as an electrolytic solution. A unique Pummerer-type mechanism uta fluorosulfonium ions was proposed for this anodic fluorination by comparison with anodic alpha-methoxylation previously studied.
• FUCHIGAMI, TOSHIO;SHIMOJO, MORIYASU;KONNO, AKINORI;NAKAGAWA, KIYONO, J. ORG. CHEM., 55,(1990) N5, C. 6074-6075
  作者：FUCHIGAMI, TOSHIO、SHIMOJO, MORIYASU、KONNO, AKINORI、NAKAGAWA, KIYONO

  DOI：——

  日期：——
• Fuchigami Toshio, Konno Akinori, Nakagawa Kiyono, Shimojo Moriyasu, J. Org. Chem, 59 (1994) N 20, S 5937-5941
  作者：Fuchigami Toshio, Konno Akinori, Nakagawa Kiyono, Shimojo Moriyasu

  DOI：——

  日期：——