(methylthio)ethyltrimethylammonium iodide | 74484-24-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (methylthio)ethyltrimethylammonium iodide
• 英文别名: trimethyl-(2-methylsulfanyl-ethyl)-ammonium; iodide；Trimethyl-(2-methylmercapto-aethyl)-ammonium; Jodid；Methylthiocholine iodide；trimethyl(2-methylsulfanylethyl)azanium;iodide
• CAS: 74484-24-5
• 化学式: C₆H₁₆NS*I
• 分子量: 261.17
• InChiKey: NBVNNVNFGUFZMN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.94
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  sodium methylate 、 (methylthio)ethyltrimethylammonium iodide 生成 三甲胺
  参考文献：
  名称：

  Schneider, Justus Liebigs Annalen der Chemie, 1912, vol. 386, p. 340

  摘要：

  DOI：
• 作为产物：
  描述：

  N,N,N-trimethyl-2-(methylsulfinyl)ethylammonium iodide 在 高氯酸 、 sodium iodide 作用下， 以 水 为溶剂， 生成 (methylthio)ethyltrimethylammonium iodide
  参考文献：
  名称：

  Neighboring-group participation in organic redox reactions: effect of tertiary amine and pyridine groups on the kinetics and mechanism of thioether-sulfoxide interconversions

  摘要：

  DOI：

  10.1021/jo00320a002

文献信息

• Reaction of azirines with sulfur nucleophiles. 1. Treatment of 2,2-dimethyl-3-phenylazirine with ?-substituted ethanethiols
  作者：R. S. �l'kinson、A. V. Eremeev、A. F. Mishnev、Ya. Ya. Bleidelis、V. G. Semenikhina

  DOI：10.1007/bf00505897

  日期：1985.1
• OHARA, YOSHIO;AKIBA, KIN-YA;INAMOTO, NAOKI, BULL. CHEM. SOC. JAP., 1983, 56, N 5, 1508-1513
  作者：OHARA, YOSHIO、AKIBA, KIN-YA、INAMOTO, NAOKI

  DOI：——

  日期：——
• EHLKINSON, R. S.;EREMEEV, A. V.;MISHNEV, A. F.;BLEJDELIS, YA. YA.;SEMENIX+, XIMIYA GETEROTSIKL. SOEDIN., 1985, N 1, 53-58
  作者：EHLKINSON, R. S.、EREMEEV, A. V.、MISHNEV, A. F.、BLEJDELIS, YA. YA.、SEMENIX+

  DOI：——

  日期：——
• METHOD FOR PREPARING FUSION PROTEIN BY TRANS-SPLICING METHOD
  申请人：Kawakami Masayuki

  公开号：US20080187941A1

  公开（公告）日：2008-08-07

  An object to be achieved by the present invention is to provide a method that enables convenient production of a target fusion protein within a short time without constructing any expression vector. The present invention provides a method for producing a fusion protein comprising a first protein and a second protein, which comprises the steps of: introducing a nucleic acid molecule (pre-trans-splicing molecule) or a vector capable of expressing such a nucleic acid molecule into a cell expressing the first protein, wherein the nucleic acid molecule contains a gene sequence encoding the second protein and a sequence which is capable of inducing trans-splicing through binding to pre-mRNA that is generated from a region containing a gene sequence that encodes the first protein; and recovering a fusion protein comprising the first protein and the second protein generated within the cell.