N-(2-{(E)-[(Pyridin-2-yl)methylidene]amino}ethyl)acetamide | 922154-89-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-(2-{(E)-[(Pyridin-2-yl)methylidene]amino}ethyl)acetamide
• 英文别名: N-[2-(pyridin-2-ylmethylideneamino)ethyl]acetamide
• CAS: 922154-89-0
• 化学式: C₁₀H₁₃N₃O
• 分子量: 191.233
• InChiKey: DFJGWMPODJPFGL-UHFFFAOYSA-N

物化性质

• 沸点：
  413.7±25.0 °C(Predicted)
• 密度：
  1.08±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  五羰基溴铼(I) 、 N-(2-{(E)-[(Pyridin-2-yl)methylidene]amino}ethyl)acetamide 以 甲醇 、 氯仿 为溶剂， 以33%的产率得到fac-[Re(CO)3Br(MeCONHCH2CH2NCHPy)]
  参考文献：
  名称：

  Synthesis and characterization of polyamidoamine dendrimers surface-functionalized with bromotricarbonylpyridyliminerhenium(I) units

  摘要：

  A novel type of rhenium-containing dendrimers has been prepared and characterized. A series of Schiff base-terminated PAMAM dendrimers were prepared by condensing the terminal amine groups of PAMAM dendrimers with pyridine-2-carboxaldehyde. Complete condensation of the terminal amines was confirmed by H-1 NMR spectroscopy. Bromotricarbonylrhenium(I) moieties were introduced onto the surface of these modified PAMAM derivatives by refluxing with bromopentacarbonylrhenium(l). These complexes had been characterized by a variety of analytical and spectroscopic techniques and their IR, NMR, and mass spectra discussed. The crystal structure of the model compound [(CH3CONHCH2CH2N=CH-Py)ReBr(CO)(3)] confirms a facial configuration of the three carbonyl ligands. UV-Vis absorption spectroscopy suggests that the {Re(CO)(3)) moieties are quite far apart even in the second generation PAMAM dendrimers and do not interact with one another. In fact, the intensity of the metal-to-ligand (d pi-p pi(*)) charge-transfer is a linear function of the number of {Re(CO)(3)} chromophores. (c) 2006 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2006.08.094