(6-Dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetyl chloride | 860615-17-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: (6-Dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetyl chloride
• 英文别名: 2-(6-dodecyl-1,3,5,7-tetraoxopyrrolo[3,4-f]isoindol-2-yl)acetyl chloride
• CAS: 860615-17-4
• 化学式: C₂₄H₂₉ClN₂O₅
• 分子量: 460.958
• InChiKey: UGDUMHJDKCFACC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  32.0
• 可旋转键数：
  13.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  95.21
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  乙二醇 、 (6-Dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetyl chloride 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 氯仿 为溶剂， 以60%的产率得到(6-Dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetic acid 2-[2-(6-dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetoxy]-ethyl ester
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p
• 作为产物：
  描述：

  均苯四甲酸二酐 在 草酰氯 、 N,N-二甲基甲酰胺 作用下， 以 N,N-二甲基甲酰胺 、 苯 为溶剂， 反应 10.0h， 生成 (6-Dodecyl-1,3,5,7-tetraoxo-3,5,6,7-tetrahydro-1H-pyrrolo[3,4-f]isoindol-2-yl)-acetyl chloride
  参考文献：
  名称：

  First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction

  摘要：

  [GRAPHIC]The first class of zipper-shaped artificial duplexes, which are driven by multiple donor-acceptor interactions between electron-rich 1,5-dioxynaphthalene or 1,4-dioxybenzene and electron-deficient pyromellitic dimide units, have been studied in organic media by H-1 NMR, UV-vis, and vapor pressure osmometry. H-1 NMR binding investigations reveal substantial cooperativity of the donor-acceptor interaction in the duplexes.

  DOI：

  10.1021/ol034549p

文献信息

• Self-assembly of a novel series of hetero-duplexes driven by donor–acceptor interaction
  作者：Qi-Zhong Zhou、Mu-Xin Jia、Xue-Bin Shao、Li-Zhu Wu、Xi-Kui Jiang、Zhan-Ting Li、Guang-Ju Chen

  DOI：10.1016/j.tet.2005.05.039

  日期：2005.7

  The self-assembly of a novel series of donor-acceptor interaction-driven artificial hetero-duplexes in organic media has been described. Four linear compounds 1a-1d, bearing two to five electron rich 1,5-dioxynaphthalene units connected by the tetra(ethylene glycol) linker, respectively, have been prepared and used as donors, while eight compounds 2a-2d, 13-16, bearing one to four electron deficient pyromellitic diimide, 1,4,5,8-naphthalene-tetracarboxydiimide, or perylene-3,4,9,10-tetracarboxydiimide units, respectively, have been used as acceptors. The structure of the hetero-duplexes has been characterized by the H-1 NMR, UV-vis spectroscopy and vapor pressure osmometry. It is revealed that the binding stability of the duplexes vary greatly, depending on the length and structure of the monomers and also the solvent, and hetero-duplex 1d(.)2d displays a maximum association constant of ca. 1.0 x 10(4) m(-1) in chloroform. (c) 2005 Elsevier Ltd. All rights reserved.